Thyroid disorders are defined as a condition of anbnomal of thyroid function in production of thyroid hormones (Hyperthyroidsm, if over produced and hypothyroidism if under produced).
Types of food to prevent and treat thyroid disorders
1. Skin and seed of grape
In the study of resveratrol, the main ingredient found in skin and seed of grape and its impact on aging and thyroid function, showed that resveratrol is believed to regulate several biological processes, mainly
metabolism and aging, by modulating the mammalian silent information
regulator 1 (SIRT1) of the sirtuin family. Resveratrol may arrest, among
various tumors, cell growth in both papillary and follicular thyroid
cancer by activation of the mitogen-activated protein kinase (MAPK)
signal transduction pathway as well as increase of p53 and its
phosphorylation. Finally, resveratrol also influences thyroid
function by enhancing iodide trapping and, by increasing TSH secretion
via activation of sirtuins and the phosphatidylinositol- 4-phosphate 5
kinase γ (PIP5Kγ) pathway, positively affects metabolism(1)
2. Green tea
In the comparison of the efficacy of polyphenolic flavonoids found in black and green tea in thyroid function, showed that green tea extract at 2.5 g% and 5.0 g% doses and black tea extract only at 5.0 g% dose have the potential to alter the thyroid gland physiology and architecture, that is, enlargement of thyroid gland as well as hypertrophy and/or hyperplasia of the thyroid follicles and inhibition of the activity of thyroid
peroxidase and 5(')-deiodinase I with elevated thyroidal Na+, K+-ATPase
activity along with significant decrease in serum T3 and T4, and a
parallel increase in serum thyroid stimulating hormone (TSH)(2)
3. Soy and seaweed
In the study to evaluate the relevant literature and provide the clinician guidance for advising their patients about the effects of soy on thyroid function, showed that soy foods, by inhibiting absorption, may increase the dose of thyroid hormone required by hypothyroid patients. However, hypothyroid adults need not avoid soy foods. In addition, there remains a theoretical concern based on in vitro and animal data that in individuals with compromised thyroid function and/or whose iodine intake is marginal soy foods may increase risk of developing clinical hypothyroidism(3). Others suggested that Seaweed ingestion increased I/C concentrations (P < .0001) and serum
TSH (P < .0001) (1.69 +/- 0.22 vs. 2.19 +/- 0.22 microU/mL, mean +/-
SE). Soy supplementation did not affect thyroid
end points. Seven weeks of 5 g/day seaweed supplementation was
associated with a small but statistically significant increase in TSH. Soy protein isolate supplementation was not associated with changes in serum thyroid hormone concentrations(4).
4. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21946130
(2) http://www.ncbi.nlm.nih.gov/pubmed/20801949
(3) http://www.ncbi.nlm.nih.gov/pubmed/16571087
(4) http://www.ncbi.nlm.nih.gov/pubmed/17472472
Wednesday, July 18, 2012
(Phytochemicals in) Foods to Prevent and Treat diseases -Pertussis
Pertussis (whooping cough) is a disease of uncontrollable coughing as a result of infection caused by bacteria Bordetella pertussis
Types of food to prevent and treat Pertussis
1. Green tea and black tea
In the study to evaluate the efficacy of anti bactericidal activity of tea and catechins against Bordetella pertussis, indicated that pu-erh tea killed the bacteria in a moderate way. (-) Epigallocatechin gallate (EGCg) and theaflavin digallate (TF3) showed also marked bactericidal activity. Green tea and black tea also effectively blocked the adhesion of B. pertussis to HeLa and CHO cells, whereas ECGg and TF3 could not. EGCg and TF3 markedly inactivated leuco-lymphocytosis promoting activity of pertussis toxin. Black tea showed slight but significant inactivation of the activity, whereas green tea showed no inactivation(1).
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed?term=green%20tea%20and%20pertussis
Types of food to prevent and treat Pertussis
1. Green tea and black tea
In the study to evaluate the efficacy of anti bactericidal activity of tea and catechins against Bordetella pertussis, indicated that pu-erh tea killed the bacteria in a moderate way. (-) Epigallocatechin gallate (EGCg) and theaflavin digallate (TF3) showed also marked bactericidal activity. Green tea and black tea also effectively blocked the adhesion of B. pertussis to HeLa and CHO cells, whereas ECGg and TF3 could not. EGCg and TF3 markedly inactivated leuco-lymphocytosis promoting activity of pertussis toxin. Black tea showed slight but significant inactivation of the activity, whereas green tea showed no inactivation(1).
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed?term=green%20tea%20and%20pertussis
(Phytochemicals in) Foods to Prevent and Treat diseases - Premenstrual syndrome (PMS)
Premenstrual syndrome effects over 70% to 90% of women before menopause
in the US and less for women in Southeast Asia because of their
difference in living style and social structure. The occurrence of
premenstrual syndrome (PMS) have more than doubled over the past 50
years due to the acceptance of it as a medical condition that is caused
by unhealthy diet with high in saturated food. Premenstrual syndrome
is defined as faulty function of the ovaries related to the women's
menstrual cycle, it effects a women's physical and emotional state, and
sometimes interferes with daily activities as a result of hormone
fluctuation. The syndrome occurs one to two weeks before menstruation
and then declines when the period starts.
Types of food to prevent and treat Premenstrual syndrome (PMS)
1. Wheat Germ
In the study to examine the efficacy of alpha-tocopherol supplementation in reducing specific symptoms of the premenstrual syndrome (PMS), indicated that standardized PMS questionnaires were administered in the luteal phase of the menstrual cycle to all subjects, before and after daily treatment with 400 IU d,alpha-tocopherol or placebo for three cycles. Of the 46 subjects enrolled, 41 completed the clinical trial. A significant improvement in certain affective and physical symptoms was noted in subjects treated with d,alpha-tocopherol(1).
2. Soy
In the study to identify the potential relationship between soy isoflavones and premenstrual syndrome, showed that after two cycles of ISP containing IF intervention, total symptoms (F(2,36) 8.20, P=0.000) and physical symptoms (F(2,36) 8.18, P=0.000) were significantly reduced compared with baseline after both active and placebo treatments, although differences between active and placebo treatment were non-significant. Specific premenstrual symptoms, headache (F(2,32) 4.10, P=0.026) and breast tenderness (F(2,32) 4.59, P=0.018), were reduced from baseline after soy IF, but not milk protein placebo. Cramps (F(2,32) 4.15, P=0.025) and swelling (F(2,32) 4.64, P=0.017) were significantly lower after active treatment compared with placebo. Concentrations of genistein and daidzein were increased following soy IF consumption, but equol production did not enhance symptom reduction(2).
3. Neptune Krill oil and fish oil
In the study to evaluate the effectiveness of Neptune Krill Oil (NKO) for the management of premenstrual syndrome and dysmenorrhea, showed that Neptune Krill Oil can significantly reduce dysmenorrhea and the emotional symptoms of premenstrual syndrome and is shown to be significantly more effective for the complete management of premenstrual symptoms compared to omega-3 fish oil(3).
4. Etc.
Resources
(1) http://www.ncbi.nlm.nih.gov/pubmed/3302248
(2) http://www.ncbi.nlm.nih.gov/pubmed/15975174
(3) http://www.ncbi.nlm.nih.gov/pubmed/12777162
Types of food to prevent and treat Premenstrual syndrome (PMS)
1. Wheat Germ
In the study to examine the efficacy of alpha-tocopherol supplementation in reducing specific symptoms of the premenstrual syndrome (PMS), indicated that standardized PMS questionnaires were administered in the luteal phase of the menstrual cycle to all subjects, before and after daily treatment with 400 IU d,alpha-tocopherol or placebo for three cycles. Of the 46 subjects enrolled, 41 completed the clinical trial. A significant improvement in certain affective and physical symptoms was noted in subjects treated with d,alpha-tocopherol(1).
2. Soy
In the study to identify the potential relationship between soy isoflavones and premenstrual syndrome, showed that after two cycles of ISP containing IF intervention, total symptoms (F(2,36) 8.20, P=0.000) and physical symptoms (F(2,36) 8.18, P=0.000) were significantly reduced compared with baseline after both active and placebo treatments, although differences between active and placebo treatment were non-significant. Specific premenstrual symptoms, headache (F(2,32) 4.10, P=0.026) and breast tenderness (F(2,32) 4.59, P=0.018), were reduced from baseline after soy IF, but not milk protein placebo. Cramps (F(2,32) 4.15, P=0.025) and swelling (F(2,32) 4.64, P=0.017) were significantly lower after active treatment compared with placebo. Concentrations of genistein and daidzein were increased following soy IF consumption, but equol production did not enhance symptom reduction(2).
3. Neptune Krill oil and fish oil
In the study to evaluate the effectiveness of Neptune Krill Oil (NKO) for the management of premenstrual syndrome and dysmenorrhea, showed that Neptune Krill Oil can significantly reduce dysmenorrhea and the emotional symptoms of premenstrual syndrome and is shown to be significantly more effective for the complete management of premenstrual symptoms compared to omega-3 fish oil(3).
4. Etc.
Resources
(1) http://www.ncbi.nlm.nih.gov/pubmed/3302248
(2) http://www.ncbi.nlm.nih.gov/pubmed/15975174
(3) http://www.ncbi.nlm.nih.gov/pubmed/12777162
Tuesday, July 17, 2012
(Phytochemicals in) Foods to Prevent and Treat diseases - Pelvic inflammatory disease
Pelvic inflammation disease (PID) is defined as condition caused by inflammation or infection of the female uterus, fallopian tubes, and/or ovaries as a result of scars
and adhesion in the pelvic which in turn may prevent the implantation
of egg during natural pregnancy process. It affects over 1 million
women in U.S. every month and most of them are in their teen and
twenties and over 100,000 women become infertile in the US alone each year.
Types of food to prevent and treat Pelvic inflammatory disease
1. Turmeric
According to the study of evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation by Satoskar RR, Shah SJ, Shenoy SG., poated in US National Library of Medicine National Institutes of Health, researchers wrote that In this model of postoperative inflammation, the anti-inflammatory activity of curcumin (diferuloyl methane) was investigated in comparison with phenylbutazone and placebo. Phenylbutazone and curcumin produced a better anti-inflammatory response than placebo(1).
2. Soy
In the study of Changes in the anti-inflammatory activity of soy isoflavonoidgenistein versus genistein incorporated in two types of cyclodextrin derivatives, found that genistein is an active anti-inflammatory phytocompound andits complexation with hydrophilic beta-cyclodextrin derivatives leads to a stronger antiinflammatoryactivity(2).
3. Skin and seed of grape
Anti-inflammatory effects of resveratrol and its potential use in therapy of immune-mediated diseases review provides an up-to-date discussion on recent advances regarding anti-inflammatory effects of resveratrol, mechanisms of action, and its potential for therapeutic use(3).
4. Garlic
In the study of Sulfur compounds isolated from garlic exert anti-inflammatory properties, suggested that thiacremonone exerted its anti-inflammatory and anti-arthritic properties through the inhibition of NF-kappaB activation via interaction with the sulfhydryl group of NF-kappaB molecules, and thus could be a useful agent for the treatment of inflammatory and arthritic diseases(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/3546166
(2) http://www.ncbi.nlm.nih.gov/pubmed/22716299
(3) http://www.ncbi.nlm.nih.gov/pubmed/22587021
(4) http://www.ncbi.nlm.nih.gov/pubmed/19788760
Types of food to prevent and treat Pelvic inflammatory disease
1. Turmeric
According to the study of evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation by Satoskar RR, Shah SJ, Shenoy SG., poated in US National Library of Medicine National Institutes of Health, researchers wrote that In this model of postoperative inflammation, the anti-inflammatory activity of curcumin (diferuloyl methane) was investigated in comparison with phenylbutazone and placebo. Phenylbutazone and curcumin produced a better anti-inflammatory response than placebo(1).
2. Soy
In the study of Changes in the anti-inflammatory activity of soy isoflavonoidgenistein versus genistein incorporated in two types of cyclodextrin derivatives, found that genistein is an active anti-inflammatory phytocompound andits complexation with hydrophilic beta-cyclodextrin derivatives leads to a stronger antiinflammatoryactivity(2).
3. Skin and seed of grape
Anti-inflammatory effects of resveratrol and its potential use in therapy of immune-mediated diseases review provides an up-to-date discussion on recent advances regarding anti-inflammatory effects of resveratrol, mechanisms of action, and its potential for therapeutic use(3).
4. Garlic
In the study of Sulfur compounds isolated from garlic exert anti-inflammatory properties, suggested that thiacremonone exerted its anti-inflammatory and anti-arthritic properties through the inhibition of NF-kappaB activation via interaction with the sulfhydryl group of NF-kappaB molecules, and thus could be a useful agent for the treatment of inflammatory and arthritic diseases(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/3546166
(2) http://www.ncbi.nlm.nih.gov/pubmed/22716299
(3) http://www.ncbi.nlm.nih.gov/pubmed/22587021
(4) http://www.ncbi.nlm.nih.gov/pubmed/19788760
(Phytochemicals in) Foods to Prevent and Treat diseases - Parkinson's disease
Parkinson's disease is defined as a health condition associated to the
depletion of dopamine in the corpus striatum as a result of neuron loss
in the substantianigra. The disease most often occurs in the middle age
and beyond.
Types of food to prevent and treat Parkinson's disease
1. Fish
In the review the use of antioxidants and other supplements for the prevention and treatment of Parkinson's disease (PD), showed that antioxidants and supplements appear to have a limited role in the prevention or treatment of PD. Of those reviewed here, CoQ10 appears to provide some minor treatment benefits(1).
2. Green tea
In the study of Differential effects of black versus green tea on risk of Parkinson's disease in the Singapore Chinese Health Study, found that total caffeine intake was inversely related to Parkinson's disease risk (p for trend = 0.002); the relative risk for the highest versus lowest quartile was 0.55 (95% confidence interval: 0.35, 0.88). Black tea, a caffeine-containing beverage, showed an inverse association with Parkinson's disease risk that was not confounded by total caffeine intake or tobacco smoking (p for trend = 0.0006; adjusted relative risk for the highest vs. lowest tertile of intake = 0.29, 95% confidence interval: 0.13, 0.67). Green tea drinking was unrelated to Parkinson's disease risk. Diet had no strong influence on risk. Ingredients of black tea other than caffeine appear to be responsible for the beverage's inverse association with Parkinson's disease(2).
3. Skin and seed of grapes
In the study to investigate the neuroprotective effects of resveratrol on 6-hydroxydopamine (6-OHDA)-induced Parkinson's disease in rats. 6-OHDA-induced Parkinson's disease rat model involves chronic inflammation, mitochondrial dysfunction, and oxidative stress, and the loss of the dopaminergic neurons in the substantia nigra is the predominant lesion, found that resveratrol treatment also significantly decreased the levels of COX-2 and TNF-alpha mRNA in the substantia nigra as detected by real-time RT-PCR. COX-2 protein expression in the substantia nigra was also decreased as evidenced by Western blotting. These results demonstrate that resveratrol exerts a neuroprotective effect on 6-OHDA-induced Parkinson's disease rat model, and this protection is related to the reduced inflammatory reaction(3)
4. Soy
In the study of the protective effect of the bioflavonoid quercetin on behaviors, antioxidases, and neurotransmitters in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-(MPTP-) induced Parkinson's disease (PD, show that quercetin treatment markedly improves the motor balance and coordination of MPTP-treated mice. Significant increases were observed in the activities of glutathione peroxidase (GPx), superoxide dismutase (SOD), and Na(+), K(+)-ATPase, AchE, the content of dopamine (DA) in the quercetin plus MPTP groups compared to those in the MPTP group. Significant reduction the 4-hydroxy-2-nonenal (4-HNE) immunoreactivity in striatum of brains was observed in the quercetin plus MPTP groups in comparison to the MPTP group. Taken together, we propose that quercetin has shown antiparkinsonian properties in our studies. More work is needed to explore detailed mechanisms of action(4)
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16622156
(2) http://www.ncbi.nlm.nih.gov/pubmed/18156141
(3) http://www.ncbi.nlm.nih.gov/pubmed/18940189
(4) http://www.ncbi.nlm.nih.gov/pubmed/22454690
Types of food to prevent and treat Parkinson's disease
1. Fish
In the review the use of antioxidants and other supplements for the prevention and treatment of Parkinson's disease (PD), showed that antioxidants and supplements appear to have a limited role in the prevention or treatment of PD. Of those reviewed here, CoQ10 appears to provide some minor treatment benefits(1).
2. Green tea
In the study of Differential effects of black versus green tea on risk of Parkinson's disease in the Singapore Chinese Health Study, found that total caffeine intake was inversely related to Parkinson's disease risk (p for trend = 0.002); the relative risk for the highest versus lowest quartile was 0.55 (95% confidence interval: 0.35, 0.88). Black tea, a caffeine-containing beverage, showed an inverse association with Parkinson's disease risk that was not confounded by total caffeine intake or tobacco smoking (p for trend = 0.0006; adjusted relative risk for the highest vs. lowest tertile of intake = 0.29, 95% confidence interval: 0.13, 0.67). Green tea drinking was unrelated to Parkinson's disease risk. Diet had no strong influence on risk. Ingredients of black tea other than caffeine appear to be responsible for the beverage's inverse association with Parkinson's disease(2).
3. Skin and seed of grapes
In the study to investigate the neuroprotective effects of resveratrol on 6-hydroxydopamine (6-OHDA)-induced Parkinson's disease in rats. 6-OHDA-induced Parkinson's disease rat model involves chronic inflammation, mitochondrial dysfunction, and oxidative stress, and the loss of the dopaminergic neurons in the substantia nigra is the predominant lesion, found that resveratrol treatment also significantly decreased the levels of COX-2 and TNF-alpha mRNA in the substantia nigra as detected by real-time RT-PCR. COX-2 protein expression in the substantia nigra was also decreased as evidenced by Western blotting. These results demonstrate that resveratrol exerts a neuroprotective effect on 6-OHDA-induced Parkinson's disease rat model, and this protection is related to the reduced inflammatory reaction(3)
4. Soy
In the study of the protective effect of the bioflavonoid quercetin on behaviors, antioxidases, and neurotransmitters in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-(MPTP-) induced Parkinson's disease (PD, show that quercetin treatment markedly improves the motor balance and coordination of MPTP-treated mice. Significant increases were observed in the activities of glutathione peroxidase (GPx), superoxide dismutase (SOD), and Na(+), K(+)-ATPase, AchE, the content of dopamine (DA) in the quercetin plus MPTP groups compared to those in the MPTP group. Significant reduction the 4-hydroxy-2-nonenal (4-HNE) immunoreactivity in striatum of brains was observed in the quercetin plus MPTP groups in comparison to the MPTP group. Taken together, we propose that quercetin has shown antiparkinsonian properties in our studies. More work is needed to explore detailed mechanisms of action(4)
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16622156
(2) http://www.ncbi.nlm.nih.gov/pubmed/18156141
(3) http://www.ncbi.nlm.nih.gov/pubmed/18940189
(4) http://www.ncbi.nlm.nih.gov/pubmed/22454690
(Phytochemicals in) Foods to Prevent and Treat diseases - Otitis media (middle ear infection)
Otitis media is defined as an acute or chronic condition of middle ear infection, effecting mostly infants and young children.
Types of food to prevent and treat Otitis media
1. Orange peel
In the study to investigate the Effect of orange peel essential oil on oxidative stress in AOM animals
showed that orange peel essential oil treatment could decrease serum and cochlea malondialdehyde (MDA), immunoglobulins A (IgA), immunoglobulins G (IgG), immunoglobulins M (IgM) levels and increase antioxidant enzymes activitie and concluded that orange peel essential oil treatment could decrease oxidative injury in acute otitis media rats(1).
2. Carrot and tomato
In the study to investigate therapeutic role of tvitamin A on healing of middle ear mucosa in experimental acute otitis media (AOM), showed that Pretreatment with vitamin A increases antioxidant enzyme activities and reduces formation of NO and MDA. Vitamin A may be considered as an additional medicament for the medical treatment of AOM(2).
3. Garlic and onions
In the study to evaluate the effects of GSH treatment on chronic otitis media with effusion (OME), found that three months after therapy improvement had occurred in 66.6% of patients in the GSH-treated group and in 8% of the control subjects (P <.01)(3).
4. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22342737
(2) http://www.ncbi.nlm.nih.gov/pubmed/17303254
(3) http://www.ncbi.nlm.nih.gov/pubmed/11568588
Types of food to prevent and treat Otitis media
1. Orange peel
In the study to investigate the Effect of orange peel essential oil on oxidative stress in AOM animals
showed that orange peel essential oil treatment could decrease serum and cochlea malondialdehyde (MDA), immunoglobulins A (IgA), immunoglobulins G (IgG), immunoglobulins M (IgM) levels and increase antioxidant enzymes activitie and concluded that orange peel essential oil treatment could decrease oxidative injury in acute otitis media rats(1).
2. Carrot and tomato
In the study to investigate therapeutic role of tvitamin A on healing of middle ear mucosa in experimental acute otitis media (AOM), showed that Pretreatment with vitamin A increases antioxidant enzyme activities and reduces formation of NO and MDA. Vitamin A may be considered as an additional medicament for the medical treatment of AOM(2).
3. Garlic and onions
In the study to evaluate the effects of GSH treatment on chronic otitis media with effusion (OME), found that three months after therapy improvement had occurred in 66.6% of patients in the GSH-treated group and in 8% of the control subjects (P <.01)(3).
4. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22342737
(2) http://www.ncbi.nlm.nih.gov/pubmed/17303254
(3) http://www.ncbi.nlm.nih.gov/pubmed/11568588
(Phytochemicals in) Foods to Prevent and Treat diseases - Osteoporosis
Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of lossing of bone density over a long period of time.
Types of food to prevent and treat Osteoporosis
1. Green tea
In the study to investigate whether black tea polyphenol, theaflavin-3,3'-digallate (TFDG) and green tea, epigallocatechin-3-gallate (EGCG)affect MMP activity and osteoclast formation and differentiation in vitro, showed that TFDG and EGCG inhibited the formation and differentiation of osteoclasts via inhibition of MMPs. TFDG may suppress actin ring formation more effectively than EGCG. Thus, TFDG and EGCG may be suitable agents or lead compounds for the treatment of bone resorption diseases(1).
2. Soy
In the study to clarify the effect of ingesting soy isoflavone extracts (not soy protein or foods containing isoflavones) on bone mineral density (BMD) in menopausal women, found that the varying effects of isoflavones on spine BMD across trials might be associated with study characteristics of intervention duration (6 vs. 12 months), region of participant (Asian vs. Western), and basal BMD (normal bone mass vs. osteopenia or osteoporosis). No significant effects on femoral neck, hip total, and trochanter BMD were found. Soy isoflavone extract supplements increased lumbar spine BMD in menopausal women(2).
3. Orange juice
In the study to evaluate the possible variations in antioxidant enzymes, lipid peroxidation and erythrocyte deformability in experimentally induced osteoporosis in female rats and to assess the effects of vitamin C supplementation on those variations, indicated that BMD was significantly lower in the group O than in the group C (p = 0.015), whereas it was significantly higher in the group OVC than in the group O (p = 0.003). MDA activity was significantly higher in the group O than in the group C (p = 0.032), whereas it was significantly lower in the group OVC than in the group O (p = 0.025). SOD activity was significantly higher in the group O than in the group C (p = 0.032). Erythrocyte deformability was significantly higher in the group O than in the group C and OVC (p = 0.008, p = 0.021, respectively)(3).
4. Milk thistle seeds
In the study to investigate that silibinin had bone-forming and osteoprotective effects in in vitro cell systems of murine osteoblastic MC3T3-E1 cells and RAW 264.7 murine macrophages, found that that silibinin retarded tartrate-resistant acid phosphatase and cathepsin K induction and matrix metalloproteinase-9 activity elevated by RANKL through disturbing TRAF6-c-Src signaling pathways. These results demonstrate that silibinin was a potential therapeutic agent promoting bone-forming osteoblastogenesis and encumbering osteoclastic bone resorption(4).
5. Skin and seed of grape
In the study to investigate the molecular mechanism of how resveratrol can modulate the lineage commitment of human mesenchymal stem cells to osteogenesis other than adipogenesis, showed that
resveratrol promoted spontaneous osteogenesis but prevented adipogenesis in human embryonic stem cell-derived mesenchymal progenitors. Resveratrol upregulated the expression of osteo-lineage genes RUNX2 and osteocalcin while suppressing adipo-lineage genes PPARγ2 and LEPTIN in adipogenic medium. Furthermore, the osteogenic effect of resveratrol was mediated mainly through SIRT1/FOXO3A with a smaller contribution from the estrogenic pathway(5).
6. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22186621
(2) http://www.ncbi.nlm.nih.gov/pubmed/20199985
(3) http://www.ncbi.nlm.nih.gov/pubmed/22180984
(4) http://www.ncbi.nlm.nih.gov/pubmed/21898547
(5) http://www.ncbi.nlm.nih.gov/pubmed/21713995
Types of food to prevent and treat Osteoporosis
1. Green tea
In the study to investigate whether black tea polyphenol, theaflavin-3,3'-digallate (TFDG) and green tea, epigallocatechin-3-gallate (EGCG)affect MMP activity and osteoclast formation and differentiation in vitro, showed that TFDG and EGCG inhibited the formation and differentiation of osteoclasts via inhibition of MMPs. TFDG may suppress actin ring formation more effectively than EGCG. Thus, TFDG and EGCG may be suitable agents or lead compounds for the treatment of bone resorption diseases(1).
2. Soy
In the study to clarify the effect of ingesting soy isoflavone extracts (not soy protein or foods containing isoflavones) on bone mineral density (BMD) in menopausal women, found that the varying effects of isoflavones on spine BMD across trials might be associated with study characteristics of intervention duration (6 vs. 12 months), region of participant (Asian vs. Western), and basal BMD (normal bone mass vs. osteopenia or osteoporosis). No significant effects on femoral neck, hip total, and trochanter BMD were found. Soy isoflavone extract supplements increased lumbar spine BMD in menopausal women(2).
3. Orange juice
In the study to evaluate the possible variations in antioxidant enzymes, lipid peroxidation and erythrocyte deformability in experimentally induced osteoporosis in female rats and to assess the effects of vitamin C supplementation on those variations, indicated that BMD was significantly lower in the group O than in the group C (p = 0.015), whereas it was significantly higher in the group OVC than in the group O (p = 0.003). MDA activity was significantly higher in the group O than in the group C (p = 0.032), whereas it was significantly lower in the group OVC than in the group O (p = 0.025). SOD activity was significantly higher in the group O than in the group C (p = 0.032). Erythrocyte deformability was significantly higher in the group O than in the group C and OVC (p = 0.008, p = 0.021, respectively)(3).
4. Milk thistle seeds
In the study to investigate that silibinin had bone-forming and osteoprotective effects in in vitro cell systems of murine osteoblastic MC3T3-E1 cells and RAW 264.7 murine macrophages, found that that silibinin retarded tartrate-resistant acid phosphatase and cathepsin K induction and matrix metalloproteinase-9 activity elevated by RANKL through disturbing TRAF6-c-Src signaling pathways. These results demonstrate that silibinin was a potential therapeutic agent promoting bone-forming osteoblastogenesis and encumbering osteoclastic bone resorption(4).
5. Skin and seed of grape
In the study to investigate the molecular mechanism of how resveratrol can modulate the lineage commitment of human mesenchymal stem cells to osteogenesis other than adipogenesis, showed that
resveratrol promoted spontaneous osteogenesis but prevented adipogenesis in human embryonic stem cell-derived mesenchymal progenitors. Resveratrol upregulated the expression of osteo-lineage genes RUNX2 and osteocalcin while suppressing adipo-lineage genes PPARγ2 and LEPTIN in adipogenic medium. Furthermore, the osteogenic effect of resveratrol was mediated mainly through SIRT1/FOXO3A with a smaller contribution from the estrogenic pathway(5).
6. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22186621
(2) http://www.ncbi.nlm.nih.gov/pubmed/20199985
(3) http://www.ncbi.nlm.nih.gov/pubmed/22180984
(4) http://www.ncbi.nlm.nih.gov/pubmed/21898547
(5) http://www.ncbi.nlm.nih.gov/pubmed/21713995
(Phytochemicals in) Foods to Prevent and Treat diseases - Obesity
Obesity is defined as a medical condition of excess
body fat has accumulated overtime, while overweight is a condition
of excess body weight relatively to the height. According to
the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered
over weight, while a BMI of over 30 is an indication of
obesity. According to the statistic, 68% of American population
are either overweight or obese.
Types of food to prevent and treat Obesity
1. Green tea
In the study to to investigate the antiobesity effect of (-)-epigallocatechin-3-gallate (EGCG) in diet-induced obese mice, showed that green tea EGCG effectively reduces adipose tissue mass and ameliorates plasma lipid profiles in high-fat diet-induced obese mice. These effects might be at least partially mediated via regulation of the expression of multiple genes involved in adipogenesis, lipolysis, beta-oxidation and thermogenesis in white adipose tissue(1).
2. Soy
In the study of Role of dietary soy protein in obesity, researchers at the George Washington University Medical Center, indicated that there were an increasing body of literature suggests that soy protein and its isoflavones may have a beneficial role in obesity. Several nutritional intervention studies in animals and humans indicate that consumption of soy protein reduces body weight and fat mass in addition to lowering plasma cholesterol and triglycerides. In animal models of obesity, soy protein ingestion limits or reduces body fat accumulation and improves insulin resistance, the hallmark of human obesity. In obese humans, dietary soy protein also reduces body weight and body fat mass in addition to reducing plasma lipids(2).
3. Fish oil
In the study to establish whether there is a correlation between basal CoQ10 plasma concentration and the ratio of lipid parameters to CoQ10 in obese children, showed that he lowest correlation was between plasma concentration of CoQ10-OX and the ratio of LDL Chol/CoQ10 , as well as between CoQ10-OX and the ratio of TAG/CoQ10 in obese children.Conclusion: An increase of the ratios of lipid parameters to CoQ10 is associated with child obesity and could be used as biomarkers of early complications in the development of obesity in children(3).
4. Flax seed
In the study to evaluate the beneficial effects of soy protein and flaxseed meal on hypertriglyceridemia and liver steatosis associated with obesity and diabetes. We compared the effects of dietary soy protein and flaxseed meal with that of casein on plasma and liver lipids in a genetic model of obesity, found that
he marked hypotriglyceridemic and hypocholesterolemic effects of flaxseed meal may have important therapeutic implications in patients with hypertriglyceridemia and hypercholesterolemia and deserve further study in humans with these disorders. Flaxseed meal supplementation may provide a new therapeutic strategy to reduce hypertriglyceridemia and fatty liver(4).
5. Turmeric
In the study to investigate the effect of curcumin, the major polyphenol in turmeric spice, on angiogenesis, adipogenesis, differentiation, apoptosis, and gene expression involved in lipid and energy metabolism in 3T3-L1 adipocyte in cell culture systems and on body weight gain and adiposity in mice, found that in vivo effect of curcumin on the expression of these enzymes was also confirmed by real-time RT-PCR in subcutaneous adipose tissue. In addition, curcumin significantly lowered serum cholesterol and expression of PPARgamma and CCAAT/enhancer binding protein alpha, 2 key transcription factors in adipogenesis and lipogenesis. The curcumin suppression of angiogenesis in adipose tissue together with its effect on lipid metabolism in adipocytes may contribute to lower body fat and body weight gain(5).
6. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/19390166
(2) http://www.ncbi.nlm.nih.gov/pubmed/17396158
(3) http://www.ncbi.nlm.nih.gov/pubmed/22380497
(4) http://www.ncbi.nlm.nih.gov/pubmed/12672712
(5) http://www.ncbi.nlm.nih.gov/pubmed/19297423
Types of food to prevent and treat Obesity
1. Green tea
In the study to to investigate the antiobesity effect of (-)-epigallocatechin-3-gallate (EGCG) in diet-induced obese mice, showed that green tea EGCG effectively reduces adipose tissue mass and ameliorates plasma lipid profiles in high-fat diet-induced obese mice. These effects might be at least partially mediated via regulation of the expression of multiple genes involved in adipogenesis, lipolysis, beta-oxidation and thermogenesis in white adipose tissue(1).
2. Soy
In the study of Role of dietary soy protein in obesity, researchers at the George Washington University Medical Center, indicated that there were an increasing body of literature suggests that soy protein and its isoflavones may have a beneficial role in obesity. Several nutritional intervention studies in animals and humans indicate that consumption of soy protein reduces body weight and fat mass in addition to lowering plasma cholesterol and triglycerides. In animal models of obesity, soy protein ingestion limits or reduces body fat accumulation and improves insulin resistance, the hallmark of human obesity. In obese humans, dietary soy protein also reduces body weight and body fat mass in addition to reducing plasma lipids(2).
3. Fish oil
In the study to establish whether there is a correlation between basal CoQ10 plasma concentration and the ratio of lipid parameters to CoQ10 in obese children, showed that he lowest correlation was between plasma concentration of CoQ10-OX and the ratio of LDL Chol/CoQ10 , as well as between CoQ10-OX and the ratio of TAG/CoQ10 in obese children.Conclusion: An increase of the ratios of lipid parameters to CoQ10 is associated with child obesity and could be used as biomarkers of early complications in the development of obesity in children(3).
4. Flax seed
In the study to evaluate the beneficial effects of soy protein and flaxseed meal on hypertriglyceridemia and liver steatosis associated with obesity and diabetes. We compared the effects of dietary soy protein and flaxseed meal with that of casein on plasma and liver lipids in a genetic model of obesity, found that
he marked hypotriglyceridemic and hypocholesterolemic effects of flaxseed meal may have important therapeutic implications in patients with hypertriglyceridemia and hypercholesterolemia and deserve further study in humans with these disorders. Flaxseed meal supplementation may provide a new therapeutic strategy to reduce hypertriglyceridemia and fatty liver(4).
5. Turmeric
In the study to investigate the effect of curcumin, the major polyphenol in turmeric spice, on angiogenesis, adipogenesis, differentiation, apoptosis, and gene expression involved in lipid and energy metabolism in 3T3-L1 adipocyte in cell culture systems and on body weight gain and adiposity in mice, found that in vivo effect of curcumin on the expression of these enzymes was also confirmed by real-time RT-PCR in subcutaneous adipose tissue. In addition, curcumin significantly lowered serum cholesterol and expression of PPARgamma and CCAAT/enhancer binding protein alpha, 2 key transcription factors in adipogenesis and lipogenesis. The curcumin suppression of angiogenesis in adipose tissue together with its effect on lipid metabolism in adipocytes may contribute to lower body fat and body weight gain(5).
6. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/19390166
(2) http://www.ncbi.nlm.nih.gov/pubmed/17396158
(3) http://www.ncbi.nlm.nih.gov/pubmed/22380497
(4) http://www.ncbi.nlm.nih.gov/pubmed/12672712
(5) http://www.ncbi.nlm.nih.gov/pubmed/19297423
(Phytochemicals in) Foods to Prevent and Treat diseases - Narcolepsy
Narcolepsy is a sleep disorder of excessive sleepiness even attacks at the daytime.
Types of foods to prevent and treat Narcolepsy
1. Low-carbohydrate, ketogenic diet (LCKD)
In the study of the effects of a low-carbohydrate, ketogenic diet (LCKD) on sleepiness and other narcolepsy symptoms, showed that the Narcolepsy Symptom Status Questionnaire (NSSQ)-Total score decreased by 18% from 161.9 to 133.5 (p = 0.0019) over 8 weeks. Patients with narcolepsy experienced modest improvements in daytime sleepiness on an LCKD(1).
2. Coffee
In the study to evaluate the wake-promoting efficacy of paraxanthine, caffeine, and a reference wake-promoting compound, modafinil, in a mice model of narcolepsy, showed that Paraxanthine, caffeine, and modafinil significantly promoted wakefulness in both WT and narcoleptic TG mice and proportionally reduced NREM and REM sleep in both genotypes. The wake-promoting potency of 100 mg/kg p.o. of paraxanthine during the light period administration roughly corresponds to that of 200 mg/kg p.o. of modafinil. The wake-promoting potency of paraxanthine is greater and longer lasting than that of the equimolar concentration of caffeine, when the drugs were administered during the light period(2).
3. Salmon (Tyrosine: 1168mg)
In the study of L-tyrosine in the treatment of narcolepsy, researchers indicated that Since the precursor of dopamine is L-tyrosine, the administration of this amino acid may prove beneficial in the treatment of narcolepsy(3).
4. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/15210901
(2) http://www.ncbi.nlm.nih.gov/pubmed/20614853
(3) http://www.ncbi.nlm.nih.gov/pubmed/2090930
Types of foods to prevent and treat Narcolepsy
1. Low-carbohydrate, ketogenic diet (LCKD)
In the study of the effects of a low-carbohydrate, ketogenic diet (LCKD) on sleepiness and other narcolepsy symptoms, showed that the Narcolepsy Symptom Status Questionnaire (NSSQ)-Total score decreased by 18% from 161.9 to 133.5 (p = 0.0019) over 8 weeks. Patients with narcolepsy experienced modest improvements in daytime sleepiness on an LCKD(1).
2. Coffee
In the study to evaluate the wake-promoting efficacy of paraxanthine, caffeine, and a reference wake-promoting compound, modafinil, in a mice model of narcolepsy, showed that Paraxanthine, caffeine, and modafinil significantly promoted wakefulness in both WT and narcoleptic TG mice and proportionally reduced NREM and REM sleep in both genotypes. The wake-promoting potency of 100 mg/kg p.o. of paraxanthine during the light period administration roughly corresponds to that of 200 mg/kg p.o. of modafinil. The wake-promoting potency of paraxanthine is greater and longer lasting than that of the equimolar concentration of caffeine, when the drugs were administered during the light period(2).
3. Salmon (Tyrosine: 1168mg)
In the study of L-tyrosine in the treatment of narcolepsy, researchers indicated that Since the precursor of dopamine is L-tyrosine, the administration of this amino acid may prove beneficial in the treatment of narcolepsy(3).
4. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/15210901
(2) http://www.ncbi.nlm.nih.gov/pubmed/20614853
(3) http://www.ncbi.nlm.nih.gov/pubmed/2090930
Monday, July 16, 2012
(Phytochemicals in) Foods to Prevent and Treat diseases - Multiple sclerosis
Multiple Sclerosis is an inflammation of central nervous system disease
in which the fatty myelin sheaths around the axons of the brain and
spinal cord are deteriorated, leading to impair of proper conduction of
nerve impulse.
Types of food to prevent and treat Multiple sclerosis
1. Green Tea
TNFalpha, an imflammatory cytokine has been associated with MS is inhibited by antioxidants of green tea, according to the artcle of Alternative Therapies for Multiple Sclerosis by David Steenblock, M.S., D.O(1). Others sugested that the combination therapy of Glatiramer acetate (GA), an immunomodulatory MS therapeutic, and the neuroprotectant epigallocatechin-3-gallate (EGCG), the main phenol in green tea, have synergistic protective effects in vitro and in the EAE model(2).
2. Skin and seed of grapes (resveratrol) and olive oil (tyrosol)
In the study to investigate whether polyphenols modulate the expression and activity of the enzymes gelatinases A (MMP-2) and B (MMP-9), involved in the pathogenesis of multiple sclerosis (MS),
indicate that the flavonoids and non-flavonoids (flavonoids quercetin (QRC) and cathechins [green tea extract (GTE)] and the non-flavonoids resveratrol (RSV) and tyrosol/hydroxytyrosol (Oliplus)) tested exert their inhibitory effect on MMPs, displaying different mechanisms of action, possibly related to their structure. Therefore, their combined use may represent a powerful tool for the down-regulation of MMPs in the course of MS(3).
3. Turmeric
In the study of Curcuminoids in Neurodegenerative Diseases, by Dr. Kim DS and research team at the Core LifeSource Inc., showed that curcuminoids found in turmeric prevent β-synuclein aggregation in PD; attenuate ROS-induced COX-2 expression in ALS; ameliorate the symptoms of MS, DE and traumatic brain injury, in addition to neurodamages caused by heavy metal poisoning(4). Others suggested that Curcumin, a dietary spice from turmeric, has outstanding anti-inflammation and neuroprotective effects(5).
4. Soy
In the study to investigate the use of genistein for the treatment of the murine model of MS showed that genistein treatment ameliorated significantly the clinical symptoms, modulating pro- and anti-inflammatory cytokines. Moreover, we analyzed the leukocyte rolling and adherence in the CNS by performing intravital microscopy. Genistein treatment resulted in decreased rolling and adhering of leukocytes as compared to the untreated group(6).
5. Etc.
Sources
(1) http://www.stemcelltherapies.org/multiple_sclerosis_3.htm
(2) http://www.ncbi.nlm.nih.gov/pubmed/22022398
(3) http://www.ncbi.nlm.nih.gov/pubmed/21207142
(4) http://www.ncbi.nlm.nih.gov/pubmed/22742420
(5) http://www.ncbi.nlm.nih.gov/pubmed/20828641
(6) http://www.ncbi.nlm.nih.gov/pubmed/18602076
Types of food to prevent and treat Multiple sclerosis
1. Green Tea
TNFalpha, an imflammatory cytokine has been associated with MS is inhibited by antioxidants of green tea, according to the artcle of Alternative Therapies for Multiple Sclerosis by David Steenblock, M.S., D.O(1). Others sugested that the combination therapy of Glatiramer acetate (GA), an immunomodulatory MS therapeutic, and the neuroprotectant epigallocatechin-3-gallate (EGCG), the main phenol in green tea, have synergistic protective effects in vitro and in the EAE model(2).
2. Skin and seed of grapes (resveratrol) and olive oil (tyrosol)
In the study to investigate whether polyphenols modulate the expression and activity of the enzymes gelatinases A (MMP-2) and B (MMP-9), involved in the pathogenesis of multiple sclerosis (MS),
indicate that the flavonoids and non-flavonoids (flavonoids quercetin (QRC) and cathechins [green tea extract (GTE)] and the non-flavonoids resveratrol (RSV) and tyrosol/hydroxytyrosol (Oliplus)) tested exert their inhibitory effect on MMPs, displaying different mechanisms of action, possibly related to their structure. Therefore, their combined use may represent a powerful tool for the down-regulation of MMPs in the course of MS(3).
3. Turmeric
In the study of Curcuminoids in Neurodegenerative Diseases, by Dr. Kim DS and research team at the Core LifeSource Inc., showed that curcuminoids found in turmeric prevent β-synuclein aggregation in PD; attenuate ROS-induced COX-2 expression in ALS; ameliorate the symptoms of MS, DE and traumatic brain injury, in addition to neurodamages caused by heavy metal poisoning(4). Others suggested that Curcumin, a dietary spice from turmeric, has outstanding anti-inflammation and neuroprotective effects(5).
4. Soy
In the study to investigate the use of genistein for the treatment of the murine model of MS showed that genistein treatment ameliorated significantly the clinical symptoms, modulating pro- and anti-inflammatory cytokines. Moreover, we analyzed the leukocyte rolling and adherence in the CNS by performing intravital microscopy. Genistein treatment resulted in decreased rolling and adhering of leukocytes as compared to the untreated group(6).
5. Etc.
Sources
(1) http://www.stemcelltherapies.org/multiple_sclerosis_3.htm
(2) http://www.ncbi.nlm.nih.gov/pubmed/22022398
(3) http://www.ncbi.nlm.nih.gov/pubmed/21207142
(4) http://www.ncbi.nlm.nih.gov/pubmed/22742420
(5) http://www.ncbi.nlm.nih.gov/pubmed/20828641
(6) http://www.ncbi.nlm.nih.gov/pubmed/18602076
(Phytochemicals in) Foods to Prevent and Treat diseases - Migraine headache
Migraine headache is one most
common headaches defined as condition of chronic neurological disorder
of moderate to severe headaches, and nausea that usually develop
gradually over 5–20 minutes and last for less than 60 minutes and
affected over 15% of the population in US alone, as a result of the
change in the brain and its surrounding blood vessels.
Foods to prevent and treat Migraine headache
Certain diet may trigger the attack of migraine headache as a result of allergic reaction in certain people, but it may be helpful to people who are experience migraine headache with no allergic effects
1. Water
Water, an essential for the body’s proper functioning, and dehydration may trigger the migraine attack. Un a study of Fifty migraineurs were asked if insufficient fluid intake could provoke their migraine attacks conducted by The City of London Migraine Clinic, twenty replied "yes," 7 were doubtfully positive, and 23 said "no." In addition 14 of 45 migraineurs at a meeting of the British Migraine association (UK) also recognized fluid deprivation as one of their migraine triggers.(E.C.1) Adding fluid deprivation to migraine patient may reduce the numbers of migraine attacks.
2. Fish oil and Olive oil
Omega-3 PUFA, from fish oil-eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been studied to consist anti-inflammatory properties of which are useful in the management of inflammatory and autoimmune diseases, including rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, lupus erythematosus, multiple sclerosis and migraine headaches.(E.C.2)
3. Broccoli
Broccoli is a very good source of magnesium and a good source of calcium. Magnesium, plays an essential in many intracellular processes and in migraine pathogenesis, low levels of magnesium may promote cortical spreading depression, hyperaggregation of platelets, affect serotonin receptor function, and influence synthesis and release of a variety of neurotransmitters of which can trigger migraine headache(B.A.8)
4. Sardines
Sardines contain measurable amount of Omega 3 fatty acid, calcium and CoQ10 of which can be helpful in reducing the frequency of migraine headache (E.B.3)(E.B.2)
5. Spinach
Spinach is an excellent source of both calcium, magnesium, vitamin B2 (riboflavin)
Riboflavin therapy supplemented may be appropriate alternatives in patients with migraine disorder as it significant decreases in headache frequency, intensity, duration and medication intake (E.C.7)
6. Mustard Greens
The World's Healthiest Foods recommends mustard greens as an excellent source of calcium and a very good source of magnesium of which are important in preventing and treating migraine headache (See E.B.1 and 2)
7. Fish
Beside rich in Omega 3 fatty acids, all fish contain more or less DL-phenylalanine, an essential amino acid of which is important for our body converts phenylalanine to tyrosine, another amino acid then to epinephrine and norepinephrine, which are important brain chemicals called neurotransmitters. Some researchers suggest that DL-phenylalanine (DLPA) appears to potentiate pain relief and also ease depression in patients receiving opiates for chronic non-malignant pain(E.C.9)
8. Etc.
Migraine & Headache Solution!
At Last A Migraine Treatment That
Can Cure Headaches FAST And For Good?
For the series of Meningitis, please visit http://diseases-researches.blogspot.ca/p/meningitis.html
For general health, please visit http://medicaladvisorjournals.blogspot.ca/p/general-health.html
Sources
(B.A.8) http://www.ncbi.nlm.nih.gov/pubmed/22426836
(E.A.1) http://www.ncbi.nlm.nih.gov/pubmed/21835022
(E.A.2) http://www.ncbi.nlm.nih.gov/pubmed/20647174
(E.A.7) http://www.ncbi.nlm.nih.gov/pubmed/12971707
(E.A.9) http://www.ncbi.nlm.nih.gov/pubmed/20464586
(E.B.1) http://www.ncbi.nlm.nih.gov/pubmed/22426836
(E.B.2) http://www.ncbi.nlm.nih.gov/pubmed/2948651
(E.B.3) http://www.ncbi.nlm.nih.gov/pubmed/17355497
Foods to prevent and treat Migraine headache
Certain diet may trigger the attack of migraine headache as a result of allergic reaction in certain people, but it may be helpful to people who are experience migraine headache with no allergic effects
1. Water
Water, an essential for the body’s proper functioning, and dehydration may trigger the migraine attack. Un a study of Fifty migraineurs were asked if insufficient fluid intake could provoke their migraine attacks conducted by The City of London Migraine Clinic, twenty replied "yes," 7 were doubtfully positive, and 23 said "no." In addition 14 of 45 migraineurs at a meeting of the British Migraine association (UK) also recognized fluid deprivation as one of their migraine triggers.(E.C.1) Adding fluid deprivation to migraine patient may reduce the numbers of migraine attacks.
2. Fish oil and Olive oil
Omega-3 PUFA, from fish oil-eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been studied to consist anti-inflammatory properties of which are useful in the management of inflammatory and autoimmune diseases, including rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, lupus erythematosus, multiple sclerosis and migraine headaches.(E.C.2)
3. Broccoli
Broccoli is a very good source of magnesium and a good source of calcium. Magnesium, plays an essential in many intracellular processes and in migraine pathogenesis, low levels of magnesium may promote cortical spreading depression, hyperaggregation of platelets, affect serotonin receptor function, and influence synthesis and release of a variety of neurotransmitters of which can trigger migraine headache(B.A.8)
4. Sardines
Sardines contain measurable amount of Omega 3 fatty acid, calcium and CoQ10 of which can be helpful in reducing the frequency of migraine headache (E.B.3)(E.B.2)
5. Spinach
Spinach is an excellent source of both calcium, magnesium, vitamin B2 (riboflavin)
Riboflavin therapy supplemented may be appropriate alternatives in patients with migraine disorder as it significant decreases in headache frequency, intensity, duration and medication intake (E.C.7)
6. Mustard Greens
The World's Healthiest Foods recommends mustard greens as an excellent source of calcium and a very good source of magnesium of which are important in preventing and treating migraine headache (See E.B.1 and 2)
7. Fish
Beside rich in Omega 3 fatty acids, all fish contain more or less DL-phenylalanine, an essential amino acid of which is important for our body converts phenylalanine to tyrosine, another amino acid then to epinephrine and norepinephrine, which are important brain chemicals called neurotransmitters. Some researchers suggest that DL-phenylalanine (DLPA) appears to potentiate pain relief and also ease depression in patients receiving opiates for chronic non-malignant pain(E.C.9)
8. Etc.
Migraine & Headache Solution!
At Last A Migraine Treatment That
Can Cure Headaches FAST And For Good?
For the series of Meningitis, please visit http://diseases-researches.blogspot.ca/p/meningitis.html
For general health, please visit http://medicaladvisorjournals.blogspot.ca/p/general-health.html
Sources
(B.A.8) http://www.ncbi.nlm.nih.gov/pubmed/22426836
(E.A.1) http://www.ncbi.nlm.nih.gov/pubmed/21835022
(E.A.2) http://www.ncbi.nlm.nih.gov/pubmed/20647174
(E.A.7) http://www.ncbi.nlm.nih.gov/pubmed/12971707
(E.A.9) http://www.ncbi.nlm.nih.gov/pubmed/20464586
(E.B.1) http://www.ncbi.nlm.nih.gov/pubmed/22426836
(E.B.2) http://www.ncbi.nlm.nih.gov/pubmed/2948651
(E.B.3) http://www.ncbi.nlm.nih.gov/pubmed/17355497
(Phytochemicals in) Foods to Prevent and Treat diseases - Meningitis
Meningitis is defined as a condition of inflammation of the protective membranes, covering the brain and spinal cord (meninges). Meningitis, a
life threaten disease, can kill and immediate action can and does save
lives.(1) Although bacterial meningitis has become an uncommon disease
in the developed
world. Unfortunately, because of limited economic resources and poor
living conditions, many developing countries are still affected by the
devastating consequences of this life-threatening systemic infection(2)
Types of food to prevent and treat Meningitis
1. Flaxseed oil is extracted from the seeds of the flax plant (Linum usitatissimum) contained both omega-3 and omega-6 fatty acids. Flaxseed oil generally contains 50% of the omega-3 fatty acid - alpha-linolenic acid and 25 % of the omega-6 fatty acid linolenic acid, 15 % of mainly monounsaturated oleic acid and trace amounts of palmitoleic acid and eicosenoic acid.
In the investigation of Omega 3 fatty acids and theirs effect on inflammation, a physiological response to tissue trauma or infection found that dietary n-3-PUFA, EPA, to inhibit this process not only revealed an unsuspected level of regulation in the migration of inflammatory leukocytes, it also contributes to our understanding of the interactions of this bioactive lipid with the inflammatory system. Moreover, it indicates the potential for novel therapeutics that target the inflammatory system with greater affinity and/or specificity than supplementing the diet with n-3-PUFAs, according to "Omega-3 Fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment" by Tull SP, Yates CM, Maskrey BH, O'Donnell VB, Madden J, Grimble RF, Calder PC, Nash GB, Rainger GE.(46)
2. Green Tea
a. Antimicrobial activities
In the investigation of Antimicrobial activities of green of the study of "Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus" by Friedman M, Henika PR, Levin CE, Mandrell RE, Kozukue N., researchers found that flavonoids in green tea has exerted its ability in protective effects against Bacillus cereus.(47)
b. Immune system
a. In the investigation of the immunomodulatory effects of decaffeinated green tea extract in rain bow of the study of "Immunomodulatory effects of decaffeinated green tea (Camellia sinensis) on the immune system of rainbow trout (Oncorhynchus mykiss)" by Sheikhzadeh N, Nofouzi K, Delazar A, Oushani AK., researchers found that showed that decaffeinated green tea in lower doses of administration could be optimum to enhance the immunity of rainbow trout(48)
3. Garlic
Garlic is the natural superfood healer for its natural antibiotic with antiviral, antifungal, anticoagulant and antiseptic properties. Garlic cooked is fine but it loses many of its health-giving powers. Raw garlic does most of its antibiotic and preventive medicines. Here are some of effective use of garlics for PROVEN DISEASE CURED.
4. Blueberry
In the investigation of Blueberry and blackberry wines commercially available in Illinois and theirs potential health benefits, found that fruit wines made from blueberries and blackberries may have potential health applications and therefore could contribute to the economy of the wine industry. Practical Application: The majority of wines are produced from grapes, but wine can also be produced from other fruits including blueberries and blackberries, which contain phenolic compounds that may contribute to human health, according to "Comparison of Chemical Composition and Antioxidant Capacity of Commercially Available Blueberry and Blackberry Wines in Illinois" by Johnson MH, Gonzalez de Mejia E.(49)
5. Shiitake mushroom
a. Immune system
Shiitake mushroom enhances the immune system in fighting against infection and disease. influenza, viruses and irregular cells growth due to it anti-tumor polysaccharide lentinan, according to "Immunoregulatory effects of the antitumor polysaccharide lentinan on Th1/Th2 balance in patients with digestive cancers" by Yoshino S, Tabata T, Hazama S, Iizuka N, Yamamoto K, Hirayama M, Tangoku A, Oka M.(50)
b. Free radicals
Shiitake mushroom contains high levels of antioxidants such as L-ergothioneine, that helps to
reduce the risk of oxidative cause of mutation in cell division and alternation, according to"Ergothioneine; antioxidant potential, physiological function and role in disease" by Cheah IK, Halliwell B.(51)
6. Etc.
Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.
For the series of Foods to prevent and treat diseases, visit http://foodspreventandtreatdiseases.blogspot.ca/p/phytochemicals-in-foods-to-prevent-and.html
For more health articles, please visit http://medicaladvisorjournals.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/15284663
(2) http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2803%2913693-8/fulltext
(46) http://www.ncbi.nlm.nih.gov/pubmed/19707265
(47) http://www.ncbi.nlm.nih.gov/pubmed/16496576
(48) http://www.ncbi.nlm.nih.gov/pubmed/21985858
(49) http://www.ncbi.nlm.nih.gov/pubmed/22182198
(50) http://www.ncbi.nlm.nih.gov/pubmed/11205205
(51) http://www.ncbi.nlm.nih.gov/pubmed/22001064
Types of food to prevent and treat Meningitis
1. Flaxseed oil is extracted from the seeds of the flax plant (Linum usitatissimum) contained both omega-3 and omega-6 fatty acids. Flaxseed oil generally contains 50% of the omega-3 fatty acid - alpha-linolenic acid and 25 % of the omega-6 fatty acid linolenic acid, 15 % of mainly monounsaturated oleic acid and trace amounts of palmitoleic acid and eicosenoic acid.
In the investigation of Omega 3 fatty acids and theirs effect on inflammation, a physiological response to tissue trauma or infection found that dietary n-3-PUFA, EPA, to inhibit this process not only revealed an unsuspected level of regulation in the migration of inflammatory leukocytes, it also contributes to our understanding of the interactions of this bioactive lipid with the inflammatory system. Moreover, it indicates the potential for novel therapeutics that target the inflammatory system with greater affinity and/or specificity than supplementing the diet with n-3-PUFAs, according to "Omega-3 Fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment" by Tull SP, Yates CM, Maskrey BH, O'Donnell VB, Madden J, Grimble RF, Calder PC, Nash GB, Rainger GE.(46)
2. Green Tea
a. Antimicrobial activities
In the investigation of Antimicrobial activities of green of the study of "Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus" by Friedman M, Henika PR, Levin CE, Mandrell RE, Kozukue N., researchers found that flavonoids in green tea has exerted its ability in protective effects against Bacillus cereus.(47)
b. Immune system
a. In the investigation of the immunomodulatory effects of decaffeinated green tea extract in rain bow of the study of "Immunomodulatory effects of decaffeinated green tea (Camellia sinensis) on the immune system of rainbow trout (Oncorhynchus mykiss)" by Sheikhzadeh N, Nofouzi K, Delazar A, Oushani AK., researchers found that showed that decaffeinated green tea in lower doses of administration could be optimum to enhance the immunity of rainbow trout(48)
3. Garlic
Garlic is the natural superfood healer for its natural antibiotic with antiviral, antifungal, anticoagulant and antiseptic properties. Garlic cooked is fine but it loses many of its health-giving powers. Raw garlic does most of its antibiotic and preventive medicines. Here are some of effective use of garlics for PROVEN DISEASE CURED.
4. Blueberry
In the investigation of Blueberry and blackberry wines commercially available in Illinois and theirs potential health benefits, found that fruit wines made from blueberries and blackberries may have potential health applications and therefore could contribute to the economy of the wine industry. Practical Application: The majority of wines are produced from grapes, but wine can also be produced from other fruits including blueberries and blackberries, which contain phenolic compounds that may contribute to human health, according to "Comparison of Chemical Composition and Antioxidant Capacity of Commercially Available Blueberry and Blackberry Wines in Illinois" by Johnson MH, Gonzalez de Mejia E.(49)
5. Shiitake mushroom
a. Immune system
Shiitake mushroom enhances the immune system in fighting against infection and disease. influenza, viruses and irregular cells growth due to it anti-tumor polysaccharide lentinan, according to "Immunoregulatory effects of the antitumor polysaccharide lentinan on Th1/Th2 balance in patients with digestive cancers" by Yoshino S, Tabata T, Hazama S, Iizuka N, Yamamoto K, Hirayama M, Tangoku A, Oka M.(50)
b. Free radicals
Shiitake mushroom contains high levels of antioxidants such as L-ergothioneine, that helps to
reduce the risk of oxidative cause of mutation in cell division and alternation, according to"Ergothioneine; antioxidant potential, physiological function and role in disease" by Cheah IK, Halliwell B.(51)
6. Etc.
Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.
For the series of Foods to prevent and treat diseases, visit http://foodspreventandtreatdiseases.blogspot.ca/p/phytochemicals-in-foods-to-prevent-and.html
For more health articles, please visit http://medicaladvisorjournals.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/15284663
(2) http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2803%2913693-8/fulltext
(46) http://www.ncbi.nlm.nih.gov/pubmed/19707265
(47) http://www.ncbi.nlm.nih.gov/pubmed/16496576
(48) http://www.ncbi.nlm.nih.gov/pubmed/21985858
(49) http://www.ncbi.nlm.nih.gov/pubmed/22182198
(50) http://www.ncbi.nlm.nih.gov/pubmed/11205205
(51) http://www.ncbi.nlm.nih.gov/pubmed/22001064
(Phytochemicals in) Foods to Prevent and Treat diseases - Lupus
Systemic lupus
erythematosus (SLE) or Lupus is a chronic, autoimmune
disease as as a result of the development of
autoantibodies that attack the systems and organs in the
body.researchers at the indicated that saturated fatty acid palmitate,
but not unsaturated oleate, induces the
activation of the NLRP3-ASC inflammasome, causing caspase-1, IL-1β and
IL-18 production.
Types of food to prevent and treat Lupus Cerebritis
1. Deep sea fish (such as Salmon)(24)
a. Antioxidants
In the research of the antioxidant effect of vitamin E after ingestion of salmon found that that megadoses of vitamin E, far from having pro-oxidative activity, actually increase the anti-oxidative capacity of the liver, especially after ingestion of salmon oil, according to "Effects of megadoses of dietary vitamin E on the antioxidant status of rats fed lard or salmon oil" by Flader D, Brandsch C, Hirche F, Eder K
b. Vitamin D
Vitamin D not only is important to the heart health with calcium supplementation, according to "Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular event` by Wang L, Manson JE, Song Y, Sesso HD.(Ia) but also plays an vital role in epidemiological associations between vitamin D status and a large number of autoimmune and inflammatory diseases, according to "Vitamin D and inflammation" by Guillot X, Semerano L, Saidenberg-Kermanac'h N, Falgarone G, Boissier MC.
c. Omega 3 fatty acids
Omega 3 fatty acids is necessary to maintain the ratio of good and bad cholesterol, thus reducing the risk of cholesterol inflammation according to the study of "In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation" by Wang S, Wu D, Lamon-Fava S, Matthan NR, Honda KL, Lichtenstein AH., posted in PubMed (IV) and forming of free radical in the heart cells, leading to heart diseases. It also reduces the risk of plaque forming in the arterial wall, thus also decreasing the risk of stoke, according to the study of "N-3 vs. saturated fatty acids: effects on the arterial wall" by by Sudheendran S, Chang CC, Deckelbaum RJ.
d. Anti inflammationIt is said the Omega 3 fatty acids beside reduced the risk of inflammatory effects on our joints and improved blood flow, by regulating the migration of inflammatory cells that cause inflammation, but also autoimmune diseases as a result of the elevation of IL-1 and the proinflammatory leukotriene LTB(4) produced by omega-6 fatty acids, according to the study of "Omega-3 fatty acids in inflammation and autoimmune diseases" by Simopoulos AP.
e. Etc.
2. Olive oil(25)
a. Antioxidants and weight loss
In the analyzing the influence of a Mediterranean dietary pattern on plasma total antioxidant capacity (TAC) found that Mediterranean diet, especially rich in virgin olive oil, is associated with higher levels of plasma antioxidant capacity. Plasma TAC is related to a reduction in body weight after 3 years of intervention in a high cardiovascular risk population with a Mediterranean-style diet rich in virgin olive oil, according to "A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain" by Razquin C, Martinez JA, Martinez-Gonzalez MA, Mitjavila MT, Estruch R, Marti A.
b. Free radical
3. Romaine Lettuce(26)
a. Antineurodegenerative effect
In the investigation of Phenolics extracted in fresh romaine lettuce and its effect on on biological protection for neuron-like PC-12 cells found that total phenolics and total antioxidant capacity of 100 g of fresh romaine lettuce averaged 22.7 mg of gallic acid equivalents and 31.0 mg of vitamin C equivalents, respectively. The phenolic extract of romaine lettuce protected PC-12 cells against oxidative stress caused by H(2)O(2) in a dose-dependent manner. Isochlorogenic acid, one of the phenolics in romaine lettuce, showed stronger neuroprotection than the other three caffeic acid derivatives also found in the lettuce, according to "Antineurodegenerative effect of phenolic extracts and caffeic acid derivatives in romaine lettuce on neuron-like PC-12 cells" by Im SE, Yoon H, Nam TG, Heo HJ, Lee CY, Kim DO.
b. Antioxidants
In the evaluation of phenolic extracts from lettuce (baby, romaine, and iceberg cultivars) and their antioxidants effect found that the antioxidant capacity was linearly correlated with the phenolic content. The results obtained indicate that lettuce byproducts could be, from the industrial point of view, an interesting and cheap source of antioxidant phenolic extracts to funcionalize foodstuffs, according to "Lettuce and chicory byproducts as a source of antioxidant phenolic extracts" by Llorach R, Tomás-Barberán FA, Ferreres F.
c. Chlorophyll
Chlorophyll is a green pigment found in almost all plants, algae, and cyanobacteria, including romaine lettuce. It has anti-oxidant, anti-inflammatory, body cleansing and wound-healing properties, according to the study of "Effects of chlorophyll and chlorophyllin on low-dose aflatoxin B(1) pharmacokinetics in human volunteers" Jubert C, Mata J, Bench G, Dashwood R, Pereira C, Tracewell W, Turteltaub K, Williams D, Bailey G., posted in PubMed (40) researchers wrote that Chlorophyll (Chla) and chlorophyllin (CHL) were shown previously to reduce carcinogen bioavailability, biomarker damage, and tumorigenicity in trout and rats.
4. Tomato(27)
a. Antioxidative and Cancer Cell-Inhibiting Activities
In the research of Tomato ( Solanum lycopersicum ) plants synthesize nutrients, pigments, and bioactive compounds and their benefit in nutrition and human health found that Tomato extracts promoted growth in normal liver (Chang) cells, had little effect in normal lung (Hel299) cells, mildly inhibited growth of lung cancer (A549) cells, and first promoted and then, at higher concentrations, inhibited growth in lymphoma (U937) cells. The relationship of cell growth to measured constituents was not apparent, according to "Free Amino Acid and Phenolic Contents and Antioxidative and Cancer Cell-Inhibiting Activities of Extracts of 11 Greenhouse-Grown Tomato Varieties and 13 Tomato-Based Foods" by Choi SH, Kim HR, Kim HJ, Lee IS, Kozukue N, Levin CE, Friedman M.
b. Lycopene
Lycopene, one of the powerful antioxidant in tomatoes, not only helps the immune system in neutralizing the forming of free radicals in the body and according to Harvard investigation as it found that men who ate more than 10 servings tomato-based foods daily (like cooked tomatoes and tomato sauce,) had a 35 percent lower risk of developing prostate cancer than those who ate the least amount of these foods. The benefits of lycopene was more pronounced with advanced stages of prostate cancer. Also according to the study of "Chemoprevention of prostate cancer with lycopene in the TRAMP model" by Konijeti R, Henning S, Moro A, Sheikh A, Elashoff D, Shapiro A, Ku M, Said JW, Heber D, Cohen P, Aronson WJ., posted in PubMed
c. Antiseptic
Tomato is considered as antiseptic natural foods including natural antiseptic agent ascorbic acid that helps to enhance the immune system in guarding our body against the possibility of infection, sepsis, or putrefaction, according to the article of "The 7 Benefits Of Drinking Lemon Water" posted in Simple Health Cures.
5. Calciferous vegetable (such as Cabbage)(28)
a. DNA Damage
Ascorbic acid (AA), known as vitamin C, has important antioxidant vitamin has exerted the activity in preventing (imazalil)IMA-induced cause of DNA damage, according to the stuyd of "The protective role of ascorbic acid on imazalil-induced genetic damage assessed by the cytogenetic tests' by Türkez H, Aydin E.
b. Omega 3 fatty acid
Cabbage reduces the risk of cardiovascular diseases by controlling the secretion of bad cholesterol, due to high amount of Omega 3 fatty acid, according to the study of "The Omega-3 Index as a risk factor for cardiovascular diseases' by von Schacky C.
6. Blueberries(29)a. Antioxidant Capacity
In the investigation of Blueberry and blackberry wines commercially available in Illinois and theirs potential health benefits, found that fruit wines made from blueberries and blackberries may have potential health applications and therefore could contribute to the economy of the wine industry. Practical Application: The majority of wines are produced from grapes, but wine can also be produced from other fruits including blueberries and blackberries, which contain phenolic compounds that may contribute to human health, according to "Comparison of Chemical Composition and Antioxidant Capacity of Commercially Available Blueberry and Blackberry Wines in Illinois" by Johnson MH, Gonzalez de Mejia E.
b. DNA Damage
Ascorbic acid (AA), known as vitamin C, has important antioxidant vitamin has exerted the activity in preventing (imazalil)IMA-induced cause of DNA damage, according to the stuyd of "The protective role of ascorbic acid on imazalil-induced genetic damage assessed by the cytogenetic tests' by Türkez H, Aydin E.(2)
7. Tumeric(30)
c. Anti inflammatory effects
In a systematic review of the literature was to summarize the literature on the safety and anti-inflammatory activity of curcumin, found that curcumin has been demonstrated to be safe in six human trials and has demonstrated anti-inflammatory activity. It may exert its anti-inflammatory activity by inhibition of a number of different molecules that play a role in inflammation, according to "Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa)" by Chainani-Wu N.
b. Antioxidants
In the research of a literature search (PubMed) of almost 1500 papers dealing with curcumin, most from recent years, with ll available abstracts were read and pproximately 300 full papers were reviewed, found that curcumin, a component of turmeric, has been shown to be non-toxic, to have antioxidant activity, and to inhibit such mediators of inflammation as NFkappaB, cyclooxygenase-2 (COX-2), lipooxygenase (LOX), and inducible nitric oxide synthase (iNOS). Significant preventive and/or curative effects have been observed in experimental animal models of a number of diseases, including arteriosclerosis, cancer, diabetes, respiratory, hepatic, pancreatic, intestinal and gastric diseases, neurodegenerative and eye diseases, "Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases" by Bengmark S.
c. Neuroprotective effect
In the finding of the A Potential Neuroprotective Agent in treating Parkinson's Disease, found that curcumin exhibits antioxidant, anti-inflammatory and anti-cancer properties, crosses the blood-brain barrier and is neuroprotective in neurological disorders. Several studies in different experimental models of PD strongly support the clinical application of curcumin in PD. The current review explores the therapeutic potential of curcumin in PD, according to "Curcumin: A Potential Neuroprotective Agent in Parkinson's Disease" by Mythri RB, Bharath MS.
8. Ginger (31)
GINGER for OSTEOARTHRITIS:Ginger has a thytochemical called curcumin that helps reduce inflammation. It helps to protect your joints.Before we go further, we would like to remind you of cautions of using Superfood GINGER. While GINGER can help to strengthen anticoagulants such as heparin, warfarin and ticlopidine by helping your blood get less sticky but ginger raises the odd of bleeding.
9. Garlic(32)
Garlic to fight COLD and FLU. The natural compoud Allicin is released when garlic is crushed. Allicin works to fight cold, flu and other infections by breaking down into smaller chemicals called Sulfur compounds. They wake up your inmuune system, helping your body to get rid of toxins and microorganisms naturally.
10. Etc.
Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.
For the series of Foods to prevent and treat diseases, visit http://foodspreventandtreatdiseases.blogspot.ca/p/phytochemicals-in-foods-to-prevent-and.html
For more health articles, please visit http://medicaladvisorjournals.blogspot.ca
Sources
(24) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-seafoods_19.html
(25) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-nuts-seeds_8332.html
(26) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_11.html
(27) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_4522.html
(28) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_28.html
(29) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-fruits_9791.html
(30) http://medicaladvisorjournals.blogspot.ca/2012/01/world-most-popular-herbs-turmeric.html
(31) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_1048.html
(32) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_860.html
Types of food to prevent and treat Lupus Cerebritis
1. Deep sea fish (such as Salmon)(24)
a. Antioxidants
In the research of the antioxidant effect of vitamin E after ingestion of salmon found that that megadoses of vitamin E, far from having pro-oxidative activity, actually increase the anti-oxidative capacity of the liver, especially after ingestion of salmon oil, according to "Effects of megadoses of dietary vitamin E on the antioxidant status of rats fed lard or salmon oil" by Flader D, Brandsch C, Hirche F, Eder K
b. Vitamin D
Vitamin D not only is important to the heart health with calcium supplementation, according to "Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular event` by Wang L, Manson JE, Song Y, Sesso HD.(Ia) but also plays an vital role in epidemiological associations between vitamin D status and a large number of autoimmune and inflammatory diseases, according to "Vitamin D and inflammation" by Guillot X, Semerano L, Saidenberg-Kermanac'h N, Falgarone G, Boissier MC.
c. Omega 3 fatty acids
Omega 3 fatty acids is necessary to maintain the ratio of good and bad cholesterol, thus reducing the risk of cholesterol inflammation according to the study of "In vitro fatty acid enrichment of macrophages alters inflammatory response and net cholesterol accumulation" by Wang S, Wu D, Lamon-Fava S, Matthan NR, Honda KL, Lichtenstein AH., posted in PubMed (IV) and forming of free radical in the heart cells, leading to heart diseases. It also reduces the risk of plaque forming in the arterial wall, thus also decreasing the risk of stoke, according to the study of "N-3 vs. saturated fatty acids: effects on the arterial wall" by by Sudheendran S, Chang CC, Deckelbaum RJ.
d. Anti inflammationIt is said the Omega 3 fatty acids beside reduced the risk of inflammatory effects on our joints and improved blood flow, by regulating the migration of inflammatory cells that cause inflammation, but also autoimmune diseases as a result of the elevation of IL-1 and the proinflammatory leukotriene LTB(4) produced by omega-6 fatty acids, according to the study of "Omega-3 fatty acids in inflammation and autoimmune diseases" by Simopoulos AP.
e. Etc.
2. Olive oil(25)
a. Antioxidants and weight loss
In the analyzing the influence of a Mediterranean dietary pattern on plasma total antioxidant capacity (TAC) found that Mediterranean diet, especially rich in virgin olive oil, is associated with higher levels of plasma antioxidant capacity. Plasma TAC is related to a reduction in body weight after 3 years of intervention in a high cardiovascular risk population with a Mediterranean-style diet rich in virgin olive oil, according to "A 3 years follow-up of a Mediterranean diet rich in virgin olive oil is associated with high plasma antioxidant capacity and reduced body weight gain" by Razquin C, Martinez JA, Martinez-Gonzalez MA, Mitjavila MT, Estruch R, Marti A.
b. Free radical
Oleic acid
contains high amount of andioxidant that helps to improve the immune
system in fighting against the forming of free radicals cause of lipid peroxidation , according to "Effect of dietary high-oleic-acid oils that are rich in antioxidants on microsomal lipid peroxidation in rats" by Perona JS, Arcemis C, Ruiz-Gutierrez V, Catalá A.
3. Romaine Lettuce(26)
a. Antineurodegenerative effect
In the investigation of Phenolics extracted in fresh romaine lettuce and its effect on on biological protection for neuron-like PC-12 cells found that total phenolics and total antioxidant capacity of 100 g of fresh romaine lettuce averaged 22.7 mg of gallic acid equivalents and 31.0 mg of vitamin C equivalents, respectively. The phenolic extract of romaine lettuce protected PC-12 cells against oxidative stress caused by H(2)O(2) in a dose-dependent manner. Isochlorogenic acid, one of the phenolics in romaine lettuce, showed stronger neuroprotection than the other three caffeic acid derivatives also found in the lettuce, according to "Antineurodegenerative effect of phenolic extracts and caffeic acid derivatives in romaine lettuce on neuron-like PC-12 cells" by Im SE, Yoon H, Nam TG, Heo HJ, Lee CY, Kim DO.
b. Antioxidants
In the evaluation of phenolic extracts from lettuce (baby, romaine, and iceberg cultivars) and their antioxidants effect found that the antioxidant capacity was linearly correlated with the phenolic content. The results obtained indicate that lettuce byproducts could be, from the industrial point of view, an interesting and cheap source of antioxidant phenolic extracts to funcionalize foodstuffs, according to "Lettuce and chicory byproducts as a source of antioxidant phenolic extracts" by Llorach R, Tomás-Barberán FA, Ferreres F.
c. Chlorophyll
Chlorophyll is a green pigment found in almost all plants, algae, and cyanobacteria, including romaine lettuce. It has anti-oxidant, anti-inflammatory, body cleansing and wound-healing properties, according to the study of "Effects of chlorophyll and chlorophyllin on low-dose aflatoxin B(1) pharmacokinetics in human volunteers" Jubert C, Mata J, Bench G, Dashwood R, Pereira C, Tracewell W, Turteltaub K, Williams D, Bailey G., posted in PubMed (40) researchers wrote that Chlorophyll (Chla) and chlorophyllin (CHL) were shown previously to reduce carcinogen bioavailability, biomarker damage, and tumorigenicity in trout and rats.
4. Tomato(27)
a. Antioxidative and Cancer Cell-Inhibiting Activities
In the research of Tomato ( Solanum lycopersicum ) plants synthesize nutrients, pigments, and bioactive compounds and their benefit in nutrition and human health found that Tomato extracts promoted growth in normal liver (Chang) cells, had little effect in normal lung (Hel299) cells, mildly inhibited growth of lung cancer (A549) cells, and first promoted and then, at higher concentrations, inhibited growth in lymphoma (U937) cells. The relationship of cell growth to measured constituents was not apparent, according to "Free Amino Acid and Phenolic Contents and Antioxidative and Cancer Cell-Inhibiting Activities of Extracts of 11 Greenhouse-Grown Tomato Varieties and 13 Tomato-Based Foods" by Choi SH, Kim HR, Kim HJ, Lee IS, Kozukue N, Levin CE, Friedman M.
b. Lycopene
Lycopene, one of the powerful antioxidant in tomatoes, not only helps the immune system in neutralizing the forming of free radicals in the body and according to Harvard investigation as it found that men who ate more than 10 servings tomato-based foods daily (like cooked tomatoes and tomato sauce,) had a 35 percent lower risk of developing prostate cancer than those who ate the least amount of these foods. The benefits of lycopene was more pronounced with advanced stages of prostate cancer. Also according to the study of "Chemoprevention of prostate cancer with lycopene in the TRAMP model" by Konijeti R, Henning S, Moro A, Sheikh A, Elashoff D, Shapiro A, Ku M, Said JW, Heber D, Cohen P, Aronson WJ., posted in PubMed
c. Antiseptic
Tomato is considered as antiseptic natural foods including natural antiseptic agent ascorbic acid that helps to enhance the immune system in guarding our body against the possibility of infection, sepsis, or putrefaction, according to the article of "The 7 Benefits Of Drinking Lemon Water" posted in Simple Health Cures.
5. Calciferous vegetable (such as Cabbage)(28)
a. DNA Damage
Ascorbic acid (AA), known as vitamin C, has important antioxidant vitamin has exerted the activity in preventing (imazalil)IMA-induced cause of DNA damage, according to the stuyd of "The protective role of ascorbic acid on imazalil-induced genetic damage assessed by the cytogenetic tests' by Türkez H, Aydin E.
b. Omega 3 fatty acid
Cabbage reduces the risk of cardiovascular diseases by controlling the secretion of bad cholesterol, due to high amount of Omega 3 fatty acid, according to the study of "The Omega-3 Index as a risk factor for cardiovascular diseases' by von Schacky C.
6. Blueberries(29)a. Antioxidant Capacity
In the investigation of Blueberry and blackberry wines commercially available in Illinois and theirs potential health benefits, found that fruit wines made from blueberries and blackberries may have potential health applications and therefore could contribute to the economy of the wine industry. Practical Application: The majority of wines are produced from grapes, but wine can also be produced from other fruits including blueberries and blackberries, which contain phenolic compounds that may contribute to human health, according to "Comparison of Chemical Composition and Antioxidant Capacity of Commercially Available Blueberry and Blackberry Wines in Illinois" by Johnson MH, Gonzalez de Mejia E.
b. DNA Damage
Ascorbic acid (AA), known as vitamin C, has important antioxidant vitamin has exerted the activity in preventing (imazalil)IMA-induced cause of DNA damage, according to the stuyd of "The protective role of ascorbic acid on imazalil-induced genetic damage assessed by the cytogenetic tests' by Türkez H, Aydin E.(2)
7. Tumeric(30)
c. Anti inflammatory effects
In a systematic review of the literature was to summarize the literature on the safety and anti-inflammatory activity of curcumin, found that curcumin has been demonstrated to be safe in six human trials and has demonstrated anti-inflammatory activity. It may exert its anti-inflammatory activity by inhibition of a number of different molecules that play a role in inflammation, according to "Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa)" by Chainani-Wu N.
b. Antioxidants
In the research of a literature search (PubMed) of almost 1500 papers dealing with curcumin, most from recent years, with ll available abstracts were read and pproximately 300 full papers were reviewed, found that curcumin, a component of turmeric, has been shown to be non-toxic, to have antioxidant activity, and to inhibit such mediators of inflammation as NFkappaB, cyclooxygenase-2 (COX-2), lipooxygenase (LOX), and inducible nitric oxide synthase (iNOS). Significant preventive and/or curative effects have been observed in experimental animal models of a number of diseases, including arteriosclerosis, cancer, diabetes, respiratory, hepatic, pancreatic, intestinal and gastric diseases, neurodegenerative and eye diseases, "Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases" by Bengmark S.
c. Neuroprotective effect
In the finding of the A Potential Neuroprotective Agent in treating Parkinson's Disease, found that curcumin exhibits antioxidant, anti-inflammatory and anti-cancer properties, crosses the blood-brain barrier and is neuroprotective in neurological disorders. Several studies in different experimental models of PD strongly support the clinical application of curcumin in PD. The current review explores the therapeutic potential of curcumin in PD, according to "Curcumin: A Potential Neuroprotective Agent in Parkinson's Disease" by Mythri RB, Bharath MS.
8. Ginger (31)
GINGER for OSTEOARTHRITIS:Ginger has a thytochemical called curcumin that helps reduce inflammation. It helps to protect your joints.Before we go further, we would like to remind you of cautions of using Superfood GINGER. While GINGER can help to strengthen anticoagulants such as heparin, warfarin and ticlopidine by helping your blood get less sticky but ginger raises the odd of bleeding.
9. Garlic(32)
Garlic to fight COLD and FLU. The natural compoud Allicin is released when garlic is crushed. Allicin works to fight cold, flu and other infections by breaking down into smaller chemicals called Sulfur compounds. They wake up your inmuune system, helping your body to get rid of toxins and microorganisms naturally.
10. Etc.
Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.
For the series of Foods to prevent and treat diseases, visit http://foodspreventandtreatdiseases.blogspot.ca/p/phytochemicals-in-foods-to-prevent-and.html
For more health articles, please visit http://medicaladvisorjournals.blogspot.ca
Sources
(24) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-seafoods_19.html
(25) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-nuts-seeds_8332.html
(26) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_11.html
(27) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_4522.html
(28) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_28.html
(29) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-fruits_9791.html
(30) http://medicaladvisorjournals.blogspot.ca/2012/01/world-most-popular-herbs-turmeric.html
(31) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_1048.html
(32) http://medicaladvisorjournals.blogspot.ca/2011/12/world-most-healthy-foods-vegetables_860.html
(Phytochemicals in) Foods to Prevent and Treat diseases - Liver disease
Liver disease or hepatic disease is defined as a condition of damage of liver or inflammatory causes of diseases to the liver.
Types of food to prevent and treat liver disease
1. Green tea
In the study to evaluate the association between consumption of green tea and various serum markers in a Japanese population, with special reference to preventive effects of green tea against cardiovascular disease and disorders of the liver, found that Increased consumption of green tea was associated with decreased serum concentrations of total cholesterol (P for trend < 0.001) and triglyceride (P for trend = 0.02) and an increased proportion of high density lipoprotein cholesterol together with a decreased proportion of low and very low lipoprotein cholesterols (P for trend = 0.02), which resulted in a decreased atherogenic index (P for trend = 0.02). Moreover, increased consumption of green tea, especially more than 10 cups a day, was related to decreased concentrations of hepatological markers in serum, aspartate aminotransferase (P for trend = 0.06), alanine transferase (P for trend = 0.07), and ferritin (P for trend = 0.02)(1). Other researchers suggested (-)-epigallocatechin-3-gallate (EGCG) as a new inhibitor of hepatitis C virus (HCV) entry. EGCG is a flavonoid present in green tea extract belonging to the subclass of catechins(2)
2. Soy
In the stdu8y to evaluate the protective role of soy against CCl(4)-induced liver damage in rats as four experimental groups were treated for 8 weeks and included the control group,showed that Supplementation with soy succeeded to restore the elevation of liver enzymes activities and improved serum biochemical parameters. Moreover, soy supplementation improved the antioxidant enzymes, decreased lipid peroxidation, and improved the histological picture of the liver tissue. It could be concluded that soy-protein-enriched isoflavones may be a promising agent against liver diseases(3).
3. Skin and seed of grapes
Resveratrol is a plant-derived polyphenol that has a potential as a food source to extend lifespan and healthspan in model organism. In the study of the effect of resveratrol on mTOR signalingshowed that
resveratrol is an inhibitor of global protein synthesis, and that this effect is mediated through modulation of mTOR-dependent and independent signaling(4)
4. Turmeric
In the study to investigate the effects of the essential oil of Curcuma wenyujin (CWO) on growth inhibition and on the induction of apoptosis in human HepG2 cancer cells, showed that CWO exhibits an antiproliferative effect in HepG2 cells by inducing apoptosis. This growth inhibition is associated with cell cycle arrest, cytochrome C translocation, caspase 3 activation, Poly-ADP-ribose polymerase (PARP) degradation, and loss of mitochondrial membrane potential. This process involves a mitochondria-caspase dependent apoptosis pathway. As apoptosis is an important anti-cancer therapeutic target, these results suggest a potential of CWO as a chemotherapeutic agent(5).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/7711535
(2) http://www.ncbi.nlm.nih.gov/pubmed/22105803
(3) http://www.ncbi.nlm.nih.gov/pubmed/22530140
(4) http://www.ncbi.nlm.nih.gov/pubmed/22242130
(5) http://www.ncbi.nlm.nih.gov/pubmed/18666318
Types of food to prevent and treat liver disease
1. Green tea
In the study to evaluate the association between consumption of green tea and various serum markers in a Japanese population, with special reference to preventive effects of green tea against cardiovascular disease and disorders of the liver, found that Increased consumption of green tea was associated with decreased serum concentrations of total cholesterol (P for trend < 0.001) and triglyceride (P for trend = 0.02) and an increased proportion of high density lipoprotein cholesterol together with a decreased proportion of low and very low lipoprotein cholesterols (P for trend = 0.02), which resulted in a decreased atherogenic index (P for trend = 0.02). Moreover, increased consumption of green tea, especially more than 10 cups a day, was related to decreased concentrations of hepatological markers in serum, aspartate aminotransferase (P for trend = 0.06), alanine transferase (P for trend = 0.07), and ferritin (P for trend = 0.02)(1). Other researchers suggested (-)-epigallocatechin-3-gallate (EGCG) as a new inhibitor of hepatitis C virus (HCV) entry. EGCG is a flavonoid present in green tea extract belonging to the subclass of catechins(2)
2. Soy
In the stdu8y to evaluate the protective role of soy against CCl(4)-induced liver damage in rats as four experimental groups were treated for 8 weeks and included the control group,showed that Supplementation with soy succeeded to restore the elevation of liver enzymes activities and improved serum biochemical parameters. Moreover, soy supplementation improved the antioxidant enzymes, decreased lipid peroxidation, and improved the histological picture of the liver tissue. It could be concluded that soy-protein-enriched isoflavones may be a promising agent against liver diseases(3).
3. Skin and seed of grapes
Resveratrol is a plant-derived polyphenol that has a potential as a food source to extend lifespan and healthspan in model organism. In the study of the effect of resveratrol on mTOR signalingshowed that
resveratrol is an inhibitor of global protein synthesis, and that this effect is mediated through modulation of mTOR-dependent and independent signaling(4)
4. Turmeric
In the study to investigate the effects of the essential oil of Curcuma wenyujin (CWO) on growth inhibition and on the induction of apoptosis in human HepG2 cancer cells, showed that CWO exhibits an antiproliferative effect in HepG2 cells by inducing apoptosis. This growth inhibition is associated with cell cycle arrest, cytochrome C translocation, caspase 3 activation, Poly-ADP-ribose polymerase (PARP) degradation, and loss of mitochondrial membrane potential. This process involves a mitochondria-caspase dependent apoptosis pathway. As apoptosis is an important anti-cancer therapeutic target, these results suggest a potential of CWO as a chemotherapeutic agent(5).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/7711535
(2) http://www.ncbi.nlm.nih.gov/pubmed/22105803
(3) http://www.ncbi.nlm.nih.gov/pubmed/22530140
(4) http://www.ncbi.nlm.nih.gov/pubmed/22242130
(5) http://www.ncbi.nlm.nih.gov/pubmed/18666318
Sunday, July 15, 2012
(Phytochemicals in) Foods to Prevent and Treat diseases - Lactose intolerance
Lactose intolerance is a condition of the inability of the digestive system to digest lactose, a type of sugar found in milk and other dairy products.
Types of foods to prevent and treat Lactose intolerance
1. Probiotic
In the study to evaluate the efficacy of some probiotic strains for the management of lactose intolerance, indicated that our-week consumption of a probiotic combination of L casei Shirota and B breve Yakult seems to improve symptoms and decrease hydrogen production intake in lactose-intolerant patients. These effects may persist for at least 3 months after suspension of probiotic consumption(1). Other suggested that in lactose intolerants, tilactase strongly improves both lactose intolerant (LBT) results and gastrointestinal symptoms after lactose ingestion with respect to placebo. Lactobacillus reuteri also is effective but lesser than tilactase. This probiotic may represent an interesting treatment option for lactose intolerance since its use is simple and its effect may last in the time after stopping administration(1a).
2. Cereals and yogurt
In the study of Efficacy of traditional rice-lentil-yogurt diet, lactose free milk protein-based formula and soy protein formula in management of secondary lactose intolerance with acute childhood diarrhoea, Dr. Nizami SQ, and the researchers team at the Aga Khan University, Karachi, showed that No significant difference was observed in intake of diet, total calories intake, and fluid intake among the three groups. It is concluded that cheap weaning diet made of locally available cereals and yogurt can be used effectively in management of secondary lactose intolerance associated with acute childhood diarrhoea(2).
3. 12 g of lactose
There is a sufficient evidence that 12 g of lactose is tolerated by most adults with lactose malabsorption and intolerance. In the study of Randomized, controlled trials of individuals with lactose intolerance or malabsorption, Dr. Shaukat A, and scientists at the University of Minnesota and Minneapolis Veterans Affairs Medical Center showed that most individuals with presumed lactose intolerance or malabsorption can tolerate 12 to 15 g of lactose. Additional studies are needed to determine the effectiveness of lactose intolerance treatment(3).
4. Soy-based infant formulas containing isoflavones for Lactose intolerance infants
Modern soy formulas meet all nutritional requirements and safety standards of the Infant Formula Act of 1980. They are commonly used in infants with immunoglobulin E-mediated cow's milk allergy (at least 86% effective), lactose intolerance, galactosemia, and as a vegetarian human milk substitute. Largely as a result of research in animal models, concerns have been voiced regarding isoflavones in soy infant formulas in relation to nutritional adequacy, sexual development, neurobehavioral development, immune function, and thyroid disease, according to the study of Safety of soy-based infant formulas containing isoflavones: the clinical evidence(4)
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22402407
(1a) http://www.ncbi.nlm.nih.gov/pubmed/20391953
(2) http://www.ncbi.nlm.nih.gov/pubmed/8699577
(3) http://www.ncbi.nlm.nih.gov/pubmed/20404262
(4) http://www.ncbi.nlm.nih.gov/pubmed/15113975
Types of foods to prevent and treat Lactose intolerance
1. Probiotic
In the study to evaluate the efficacy of some probiotic strains for the management of lactose intolerance, indicated that our-week consumption of a probiotic combination of L casei Shirota and B breve Yakult seems to improve symptoms and decrease hydrogen production intake in lactose-intolerant patients. These effects may persist for at least 3 months after suspension of probiotic consumption(1). Other suggested that in lactose intolerants, tilactase strongly improves both lactose intolerant (LBT) results and gastrointestinal symptoms after lactose ingestion with respect to placebo. Lactobacillus reuteri also is effective but lesser than tilactase. This probiotic may represent an interesting treatment option for lactose intolerance since its use is simple and its effect may last in the time after stopping administration(1a).
2. Cereals and yogurt
In the study of Efficacy of traditional rice-lentil-yogurt diet, lactose free milk protein-based formula and soy protein formula in management of secondary lactose intolerance with acute childhood diarrhoea, Dr. Nizami SQ, and the researchers team at the Aga Khan University, Karachi, showed that No significant difference was observed in intake of diet, total calories intake, and fluid intake among the three groups. It is concluded that cheap weaning diet made of locally available cereals and yogurt can be used effectively in management of secondary lactose intolerance associated with acute childhood diarrhoea(2).
3. 12 g of lactose
There is a sufficient evidence that 12 g of lactose is tolerated by most adults with lactose malabsorption and intolerance. In the study of Randomized, controlled trials of individuals with lactose intolerance or malabsorption, Dr. Shaukat A, and scientists at the University of Minnesota and Minneapolis Veterans Affairs Medical Center showed that most individuals with presumed lactose intolerance or malabsorption can tolerate 12 to 15 g of lactose. Additional studies are needed to determine the effectiveness of lactose intolerance treatment(3).
4. Soy-based infant formulas containing isoflavones for Lactose intolerance infants
Modern soy formulas meet all nutritional requirements and safety standards of the Infant Formula Act of 1980. They are commonly used in infants with immunoglobulin E-mediated cow's milk allergy (at least 86% effective), lactose intolerance, galactosemia, and as a vegetarian human milk substitute. Largely as a result of research in animal models, concerns have been voiced regarding isoflavones in soy infant formulas in relation to nutritional adequacy, sexual development, neurobehavioral development, immune function, and thyroid disease, according to the study of Safety of soy-based infant formulas containing isoflavones: the clinical evidence(4)
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22402407
(1a) http://www.ncbi.nlm.nih.gov/pubmed/20391953
(2) http://www.ncbi.nlm.nih.gov/pubmed/8699577
(3) http://www.ncbi.nlm.nih.gov/pubmed/20404262
(4) http://www.ncbi.nlm.nih.gov/pubmed/15113975
(Phytochemicals in) Foods to Prevent and Treat diseases - Chronic Kidney disease
Chronic Kidney disease is defined as a condition of the progression loss of kidney function over period of many years. Stage of chronic kidney disease according to the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQ).
Stages Description GFR*
1. Signs of mild kidney disease but with normal or better GFR greater than 90%
2. Mild kidney disease with reduced GFR 60-89%
3. Moderate chronic renal insufficiency 30-59%
4. Severe chronic renal insufficiency 15-29%
5. End-stage renal failure less than 15%
*GFR is given in ml/min/1.73 m2
Types of foods to prevent and treat chronic kidney diseases
1. Honey
Individuals with chronic diseases are more susceptible to oxidative stress and damage because they have elevated levels of oxidants and/or reduced antioxidants. In the study of Honey: a novel antioxidant, researchers found that honey, administered alone or in combination with conventional therapy, might be a novel antioxidant in the management of chronic diseases commonly associated with oxidative stress. In view of the fact that the majority of these data emanate from animal studies, there is an urgent need to investigate this antioxidant effect of honey in human subjects with chronic or degenerative diseases(1).
2. Kombu
Kombu is a popular seafood and medicinal plant in China. In the study to exhibita new mechanism of fucoidan derivatives on CKD rats, found that the mechanism of fucoidan derivatives on the CKD rats had relationship with their antioxidant activities, the samples which could enhance the activity of antioxidant enzymes and reduce the LPO level could alleviate the symptom of CKD(2).
3. Peanuts and bean
In the study to investigate whether oxidative stress or a relative deficit of l-arginine plays a role in reducing cutaneous vasodilation in response to local heating in chronic kidney disease (CKD) in Eight patients with stage 3-4 CKD and eight age- and sex-matched healthy control (HC) subjects were instrumented with four microdialysis (MD) fibers for the local delivery of 1) Ringers solution (R), 2) 20 mM ascorbic acid (AA), 3) 10 mM l-arginine (l-Arg), and 4) 10 mM N(G)-nitro-l-arginine methyl ester (l-NAME). Red blood cell (RBC) flux was measured via laser Doppler flowmetry, showed that cutaneous microvascular function is impaired in stage 3-4 CKD and that oxidative stress and a deficit of l-arginine play a role in this impairment(3).
4. Flax seed or fish oil
In the study to elucidate whether PUFAs derived from plant or marine oils could have beneficial effects on the progression of experimental chronic renal failure (CRF), indicated that fter 30 days, we observed lower levels of sCr in the groups supplemented with PUFA when compared with the control group (FO: 0.92 ± 0.13; FXO: 1.06 ± 0.28; SO: 1.32 ± 0.47 mg/dL) and significantly slower variations of sCr (ΔsCr) in the groups treated with PUFAs (FO = 0.35 ± 0.16; FXO = 0.47 ± 0.31; OS = 0.72 ± 0.43; mg/dL, P = 0.041). Similarly, the CLcr of both of the groups that received PUFAs was significantly slower than the rats in the control group (FO: 0.45 ± 0.15; FXO: 0.60 ± 0.09; SO: 0.28 ± 0.06 mL/min/day; P = 0.01). The rats that received PUFA supplements also presented significantly less histological lesions compared with the control group(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22499188
(2) http://www.ncbi.nlm.nih.gov/pubmed/22210052
(3) http://www.ncbi.nlm.nih.gov/pubmed/21885796
(4) http://www.ncbi.nlm.nih.gov/pubmed/22752498
Stages Description GFR*
1. Signs of mild kidney disease but with normal or better GFR greater than 90%
2. Mild kidney disease with reduced GFR 60-89%
3. Moderate chronic renal insufficiency 30-59%
4. Severe chronic renal insufficiency 15-29%
5. End-stage renal failure less than 15%
*GFR is given in ml/min/1.73 m2
Types of foods to prevent and treat chronic kidney diseases
1. Honey
Individuals with chronic diseases are more susceptible to oxidative stress and damage because they have elevated levels of oxidants and/or reduced antioxidants. In the study of Honey: a novel antioxidant, researchers found that honey, administered alone or in combination with conventional therapy, might be a novel antioxidant in the management of chronic diseases commonly associated with oxidative stress. In view of the fact that the majority of these data emanate from animal studies, there is an urgent need to investigate this antioxidant effect of honey in human subjects with chronic or degenerative diseases(1).
2. Kombu
Kombu is a popular seafood and medicinal plant in China. In the study to exhibita new mechanism of fucoidan derivatives on CKD rats, found that the mechanism of fucoidan derivatives on the CKD rats had relationship with their antioxidant activities, the samples which could enhance the activity of antioxidant enzymes and reduce the LPO level could alleviate the symptom of CKD(2).
3. Peanuts and bean
In the study to investigate whether oxidative stress or a relative deficit of l-arginine plays a role in reducing cutaneous vasodilation in response to local heating in chronic kidney disease (CKD) in Eight patients with stage 3-4 CKD and eight age- and sex-matched healthy control (HC) subjects were instrumented with four microdialysis (MD) fibers for the local delivery of 1) Ringers solution (R), 2) 20 mM ascorbic acid (AA), 3) 10 mM l-arginine (l-Arg), and 4) 10 mM N(G)-nitro-l-arginine methyl ester (l-NAME). Red blood cell (RBC) flux was measured via laser Doppler flowmetry, showed that cutaneous microvascular function is impaired in stage 3-4 CKD and that oxidative stress and a deficit of l-arginine play a role in this impairment(3).
4. Flax seed or fish oil
In the study to elucidate whether PUFAs derived from plant or marine oils could have beneficial effects on the progression of experimental chronic renal failure (CRF), indicated that fter 30 days, we observed lower levels of sCr in the groups supplemented with PUFA when compared with the control group (FO: 0.92 ± 0.13; FXO: 1.06 ± 0.28; SO: 1.32 ± 0.47 mg/dL) and significantly slower variations of sCr (ΔsCr) in the groups treated with PUFAs (FO = 0.35 ± 0.16; FXO = 0.47 ± 0.31; OS = 0.72 ± 0.43; mg/dL, P = 0.041). Similarly, the CLcr of both of the groups that received PUFAs was significantly slower than the rats in the control group (FO: 0.45 ± 0.15; FXO: 0.60 ± 0.09; SO: 0.28 ± 0.06 mL/min/day; P = 0.01). The rats that received PUFA supplements also presented significantly less histological lesions compared with the control group(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22499188
(2) http://www.ncbi.nlm.nih.gov/pubmed/22210052
(3) http://www.ncbi.nlm.nih.gov/pubmed/21885796
(4) http://www.ncbi.nlm.nih.gov/pubmed/22752498
(Phytochemicals in) Foods to Prevent and Treat diseases - Jaundice
Jaundice is a condition of yellowish pigmentation of the skin and the whites of the eye as a result of either the body is producing too much, or not getting rid of bilirubin in the fat layer under the skin fast enough due to conditions of liver or gallbladder.
Types of food to prevent and treat Jaundice
1. Broccoli and spinach
Alpha-lipoic acid is found abundantly in Broccoli and spinach, In the study to assess the Application of alpha-lipoic acid in clinical practice, found that LA was shown to be hepatoprotective, to improve liver circulation and treat chronic liver diseases, including jaundice hepatitis, cirrhosis, and hepatic coma, to treat diabetes, and diabetic neuropathy to alter carbohydrate metabolism, atherosclerosis, coronary atherosclerosis and many others diseases(1).
2. Sweet lime peel
In the study to evaluate the role of bilirubin as an antioxidant in neonatal jaundice patients, showed that the ethanolic extract of sweet lime peel, administered orally at a dose of 72 microg is found to reduce the oxidative stress in erythrocytes of phenylhydrazine-induced jaundiced rats treated with phototherapy(2).
3. Guduchi, ginger and barley
in the study to assess the hepatoprotective effects of Melatonin and extract of Tinospora cordifolia in bile duct ligation induced jaundice in rats, showed that the assessment of microscopy, lab tests and the measurement of oxidative stress products indicates a marked hepatoprotective effect of those two compounds. The results allowed us to recomand the use of melatonin and Tinospora cordifolia to reduce the cholestasis's oxidative stress in human(3)
4. Ligularia fischeri
Ligularia fischeri is a well-known edible medicinal herb in Korea. In the study of antihepatotoxic effects of Ligularia fischeri var. spiciformis and the identification of the active component, 3,4-dicaffeoylquinic acid, researchers at the Kyungsung University, indicated that DCQA is a major principle for the antihepatotoxic activity of L. fischeri var. spiciformis. DCQA also partially restored bile flow and reduced total bilirubin and cholic acid concentrations in rats with ANIT-induced cholestasis. Treatment with DCQA inhibited the increase in triglyceride, cholesterol, and total lipids in DL-ethionine-induced fatty liver. These results support the traditionally held belief that this plant can be used for the treatment of jaundice and hepatic failure(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22768734
(2) http://www.ncbi.nlm.nih.gov/pubmed/19374257
(3) http://www.ncbi.nlm.nih.gov/pubmed/21698863
(4) http://www.ncbi.nlm.nih.gov/pubmed/16176146
Types of food to prevent and treat Jaundice
1. Broccoli and spinach
Alpha-lipoic acid is found abundantly in Broccoli and spinach, In the study to assess the Application of alpha-lipoic acid in clinical practice, found that LA was shown to be hepatoprotective, to improve liver circulation and treat chronic liver diseases, including jaundice hepatitis, cirrhosis, and hepatic coma, to treat diabetes, and diabetic neuropathy to alter carbohydrate metabolism, atherosclerosis, coronary atherosclerosis and many others diseases(1).
2. Sweet lime peel
In the study to evaluate the role of bilirubin as an antioxidant in neonatal jaundice patients, showed that the ethanolic extract of sweet lime peel, administered orally at a dose of 72 microg is found to reduce the oxidative stress in erythrocytes of phenylhydrazine-induced jaundiced rats treated with phototherapy(2).
3. Guduchi, ginger and barley
in the study to assess the hepatoprotective effects of Melatonin and extract of Tinospora cordifolia in bile duct ligation induced jaundice in rats, showed that the assessment of microscopy, lab tests and the measurement of oxidative stress products indicates a marked hepatoprotective effect of those two compounds. The results allowed us to recomand the use of melatonin and Tinospora cordifolia to reduce the cholestasis's oxidative stress in human(3)
4. Ligularia fischeri
Ligularia fischeri is a well-known edible medicinal herb in Korea. In the study of antihepatotoxic effects of Ligularia fischeri var. spiciformis and the identification of the active component, 3,4-dicaffeoylquinic acid, researchers at the Kyungsung University, indicated that DCQA is a major principle for the antihepatotoxic activity of L. fischeri var. spiciformis. DCQA also partially restored bile flow and reduced total bilirubin and cholic acid concentrations in rats with ANIT-induced cholestasis. Treatment with DCQA inhibited the increase in triglyceride, cholesterol, and total lipids in DL-ethionine-induced fatty liver. These results support the traditionally held belief that this plant can be used for the treatment of jaundice and hepatic failure(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22768734
(2) http://www.ncbi.nlm.nih.gov/pubmed/19374257
(3) http://www.ncbi.nlm.nih.gov/pubmed/21698863
(4) http://www.ncbi.nlm.nih.gov/pubmed/16176146
(Phytochemicals in) Foods to Prevent and Treat diseases - Irritable bowel syndrome
Irritable bowel syndrome or spastic colon is a condition which causes symptoms of chronic abdominal pain, discomfort, bloating, and alteration of bowel movement.
Types of food to prevent and treat Irritable bowel syndrome
1. Turkey
Tryptophan is a precursor of melatonin found in many foods including turkey. In the review of all clinical or non-clinical data about effects of melatonin in GI tract and IBS obtained from literature without time limit up to August 2010, showed that the results of seventeen non-clinical studies showed anxiolytic, anti-inflammatory, anti oxidative and motility regulatory effects of melatonin on GI tract. In conclusion melatonin can be a target of interest in IBS because of its potentials to regulate GI motility(1).
2. Fermented soy
In the study to evaluate (i) the effects of a phytoestrogen-rich soy germ fermented ingredient (SG) on visceral hypersensitivity, hyperpermeability and other symptoms in stressed intact female rats, (ii) the mechanisms of action involved on the basis of both estrogenic and protease inhibitor activities of SG, researchers showed that A 2-wk oral treatment with SG prevented the stress-induced hyperpermeability and visceral hypersensitivity in cyclic rats through ER activation, and blocked the increase in colonic proteolytic activity, suggesting that SG can be promising in IBS management(2).
3. Turmeric
In the study to assess the effects of turmeric (Curcuma longa) extract on irritable bowel syndrome (IBS) symptomology in otherwise healthy adults, indicated that IBS prevalence decreased significantly in both groups between screening and baseline (41% and 57%), with a further significant drop of 53% and 60% between baseline and after treatment, in the one- and two-tablet groups respectively (p < 0.001). A post-study analysis revealed abdominal pain/discomfort score reduced significantly by 22% and 25% in the one- and two-tablet group respectively, the difference tending toward significance (p = 0.071). There were significant improvements in all bar one of the IBSQOL scales of between 5% and 36% in both groups, approximately two thirds of all subjects reported an improvement in symptoms after treatment, and there was a favorable shift in self-reported bowel pattern(3).
4. Wheat bran and Partially hydrolyzed guar gum (PHGG)
In the study to investigate the effect of PHGG in IBS patients and compared it to a wheat bran diet, showed that both fiber and PHGG were effective in improving pain and bowel habits, but no difference was found between the two groups. Conversely, intention-to-treat analysis showed a significantly greater success in the PHGG group (60%) than in the fiber group (40%). Moreover, significantly more patients in the PHGG group reported a greater subjective improvement than those in the Fiber group. In conclusion, improvements in core IBS symptoms (abdominal pain and bowel habits) were observed with both bran and PHGG, but the latter was better tolerated and preferred by patients, revealing a higher probability of success than bran and a lower probability of patients abandoning the prescribed regimen, suggesting that it can increase the benefits deriving from fiber intake in IBS, making it a valid option to consider for high-fiber diet supplementation(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21128901
(2) http://www.ncbi.nlm.nih.gov/pubmed/22727545
(3) http://www.ncbi.nlm.nih.gov/pubmed/15673996
(4) http://journals.lww.com/jcge/fulltext/2009/11000/annatto,_diet,_and_the_irritable_bowel_syndrome.3.aspx
(5) http://www.ncbi.nlm.nih.gov/pubmed/12184518
Types of food to prevent and treat Irritable bowel syndrome
1. Turkey
Tryptophan is a precursor of melatonin found in many foods including turkey. In the review of all clinical or non-clinical data about effects of melatonin in GI tract and IBS obtained from literature without time limit up to August 2010, showed that the results of seventeen non-clinical studies showed anxiolytic, anti-inflammatory, anti oxidative and motility regulatory effects of melatonin on GI tract. In conclusion melatonin can be a target of interest in IBS because of its potentials to regulate GI motility(1).
2. Fermented soy
In the study to evaluate (i) the effects of a phytoestrogen-rich soy germ fermented ingredient (SG) on visceral hypersensitivity, hyperpermeability and other symptoms in stressed intact female rats, (ii) the mechanisms of action involved on the basis of both estrogenic and protease inhibitor activities of SG, researchers showed that A 2-wk oral treatment with SG prevented the stress-induced hyperpermeability and visceral hypersensitivity in cyclic rats through ER activation, and blocked the increase in colonic proteolytic activity, suggesting that SG can be promising in IBS management(2).
3. Turmeric
In the study to assess the effects of turmeric (Curcuma longa) extract on irritable bowel syndrome (IBS) symptomology in otherwise healthy adults, indicated that IBS prevalence decreased significantly in both groups between screening and baseline (41% and 57%), with a further significant drop of 53% and 60% between baseline and after treatment, in the one- and two-tablet groups respectively (p < 0.001). A post-study analysis revealed abdominal pain/discomfort score reduced significantly by 22% and 25% in the one- and two-tablet group respectively, the difference tending toward significance (p = 0.071). There were significant improvements in all bar one of the IBSQOL scales of between 5% and 36% in both groups, approximately two thirds of all subjects reported an improvement in symptoms after treatment, and there was a favorable shift in self-reported bowel pattern(3).
4. Wheat bran and Partially hydrolyzed guar gum (PHGG)
In the study to investigate the effect of PHGG in IBS patients and compared it to a wheat bran diet, showed that both fiber and PHGG were effective in improving pain and bowel habits, but no difference was found between the two groups. Conversely, intention-to-treat analysis showed a significantly greater success in the PHGG group (60%) than in the fiber group (40%). Moreover, significantly more patients in the PHGG group reported a greater subjective improvement than those in the Fiber group. In conclusion, improvements in core IBS symptoms (abdominal pain and bowel habits) were observed with both bran and PHGG, but the latter was better tolerated and preferred by patients, revealing a higher probability of success than bran and a lower probability of patients abandoning the prescribed regimen, suggesting that it can increase the benefits deriving from fiber intake in IBS, making it a valid option to consider for high-fiber diet supplementation(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21128901
(2) http://www.ncbi.nlm.nih.gov/pubmed/22727545
(3) http://www.ncbi.nlm.nih.gov/pubmed/15673996
(4) http://journals.lww.com/jcge/fulltext/2009/11000/annatto,_diet,_and_the_irritable_bowel_syndrome.3.aspx
(5) http://www.ncbi.nlm.nih.gov/pubmed/12184518
(Phytochemicals in) Foods to Prevent and Treat diseases - Insomnia
Insomnia is a sign and symptom
of sleep disorder and defined as a condition in which a person has a
difficulty falling asleep and/or staying asleep or sleep of poor
quality that can lead to substantial impairments in the quality of life
and functional capacity of an individual. Most adults have experienced
insomnia sometimes in their life. According to statistic, more than
30% of the population suffers from insomnia, one in three people suffer
from some form of insomnia during their lifetime and women suffer from
insomnia more often than men.
Types of food to prevent and treat Insomnia
1. Lemon balm leaf
Melissa officinalis L. has been shown as an anti-stress and anxiolytic agent. In the 15-day study to evaluate the efficacy of Cyracos(®)( a standardized Melissa officinalis L. extract) on stressed volunteers, who have mild-to-moderate anxiety disorders and sleep disturbances. Using clinician rating criteria, primary outcomes showed improvement of symptoms, found that Cyracos(®) reduced anxiety manifestations by 18% (p < 0.01), ameliorated anxiety-associated symptoms by 15% (p < 0.01) and lowered insomnia by 42% (p < 0.01). As much as 95% of subjects (19/20) responded to treatment, of which 70% (14/20) achieved full remission for anxiety, 85% (17/20) for insomnia, and 70% (14/20) for both(1).
2. Turkey
In the study to assess the effect of L-tryptophan in reducing sleep onset time on the first night of administration in doses ranging from 1 to 15 g, showed that L-tryptophan treatment alternates with an L-tryptophan-free interval until improvement occurs. The absence of side effects and lack of development of tolerance in long-term use are important factors in the decision to embark upon a trial of L-tryptophan treatment. In addition, L-tryptophan administration is not associated with impairment of visuomotor, cognitive, or memory performance, nor does it elevate threshold for arousal from sleep(2).
3. Saffron
In the study to evaluate the sleep-promoting activity of crocin and crocetin (Two carotenoid pigments, crocin and crocetin, are the major components responsible for the various pharmacological activities of C. sativus L. ) by monitoring the locomotor activity and electroencephalogram after administration of these components to mice, showed that Crocin (30 and 100 mg/kg) increased the total time of non-rapid eye movement (non-REM) sleep by 60 and 170%, respectively, during a 4-h period from 20:00 to 24:00 after its intraperitoneal administration at a lights-off time of 20:00. Crocetin (100 mg/kg) also increased the total time of non-REM sleep by 50% after the administration. These compounds did not change the amount of REM sleep or show any adverse effects, such as rebound insomnia, after the induction of sleep(3).
4. Kiwifruit
In the study to assess the effects of kiwifruit on sleep patterns, including sleep onset, duration, and quality in a free-living, self-controlled diet design, found that the total sleep time and sleep efficiency were significantly increased (13.4% and 5.41%, respectively). Kiwifruit consumption may improve sleep onset, duration, and efficiency in adults with self-reported sleep disturbances. Further investigation of the sleep-promoting properties of kiwifruit may be warranted(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed?term=phytochemicals%20and%20insomnia
(2) http://www.ncbi.nlm.nih.gov/pubmed/3090582
(3) http://www.ncbi.nlm.nih.gov/pubmed/22038919
(4) http://www.ncbi.nlm.nih.gov/pubmed/21669584
Types of food to prevent and treat Insomnia
1. Lemon balm leaf
Melissa officinalis L. has been shown as an anti-stress and anxiolytic agent. In the 15-day study to evaluate the efficacy of Cyracos(®)( a standardized Melissa officinalis L. extract) on stressed volunteers, who have mild-to-moderate anxiety disorders and sleep disturbances. Using clinician rating criteria, primary outcomes showed improvement of symptoms, found that Cyracos(®) reduced anxiety manifestations by 18% (p < 0.01), ameliorated anxiety-associated symptoms by 15% (p < 0.01) and lowered insomnia by 42% (p < 0.01). As much as 95% of subjects (19/20) responded to treatment, of which 70% (14/20) achieved full remission for anxiety, 85% (17/20) for insomnia, and 70% (14/20) for both(1).
2. Turkey
In the study to assess the effect of L-tryptophan in reducing sleep onset time on the first night of administration in doses ranging from 1 to 15 g, showed that L-tryptophan treatment alternates with an L-tryptophan-free interval until improvement occurs. The absence of side effects and lack of development of tolerance in long-term use are important factors in the decision to embark upon a trial of L-tryptophan treatment. In addition, L-tryptophan administration is not associated with impairment of visuomotor, cognitive, or memory performance, nor does it elevate threshold for arousal from sleep(2).
3. Saffron
In the study to evaluate the sleep-promoting activity of crocin and crocetin (Two carotenoid pigments, crocin and crocetin, are the major components responsible for the various pharmacological activities of C. sativus L. ) by monitoring the locomotor activity and electroencephalogram after administration of these components to mice, showed that Crocin (30 and 100 mg/kg) increased the total time of non-rapid eye movement (non-REM) sleep by 60 and 170%, respectively, during a 4-h period from 20:00 to 24:00 after its intraperitoneal administration at a lights-off time of 20:00. Crocetin (100 mg/kg) also increased the total time of non-REM sleep by 50% after the administration. These compounds did not change the amount of REM sleep or show any adverse effects, such as rebound insomnia, after the induction of sleep(3).
4. Kiwifruit
In the study to assess the effects of kiwifruit on sleep patterns, including sleep onset, duration, and quality in a free-living, self-controlled diet design, found that the total sleep time and sleep efficiency were significantly increased (13.4% and 5.41%, respectively). Kiwifruit consumption may improve sleep onset, duration, and efficiency in adults with self-reported sleep disturbances. Further investigation of the sleep-promoting properties of kiwifruit may be warranted(4).
5. Etc.
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed?term=phytochemicals%20and%20insomnia
(2) http://www.ncbi.nlm.nih.gov/pubmed/3090582
(3) http://www.ncbi.nlm.nih.gov/pubmed/22038919
(4) http://www.ncbi.nlm.nih.gov/pubmed/21669584
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